4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate

Base Information

Chemical Name:4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate
CAS No.:18800-74-3
Molecular Formula:C10H18N2O5
Molecular Weight:245.25
Hs Code.:2924199090
DSSTox Substance ID:DTXSID50940280
Wikidata:Q72509710
Mol file:18800-74-3.mol

Synonyms:DTXSID50940280;4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate

Suppliers and Price of 4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Iris Biotech GmbH
Boc-L-Glu-NH2
5 g
$ 438.75

Crysdot
Boc-Glu-NH2 97%
5g
$ 180.00

Crysdot
Boc-Glu-NH2 97%
1g
$ 90.00

Crysdot
Boc-Glu-NH2 97%
25g
$ 515.00

Crysdot
Boc-Glu-NH2 97%
10g
$ 280.00

chempep
Boc-Glu-NH2 >=98%
5g
$ 225.00

chempep
Boc-Glu-NH2 >=98%
25g
$ 675.00

Chem-Impex
Boc-L-glutamicacidα-amide,≥99%(HPLC) ≥99%(HPLC)
25G
$ 1735.55

Chem-Impex
Boc-L-glutamicacidα-amide,99%(HPLC) 99%(HPLC)
1G
$ 78.40

Chem-Impex
Boc-L-glutamicacidα-amide,99%(HPLC) 99%(HPLC)
5G
$ 347.20

Total 41 raw suppliers

Chemical Property of 4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate

Chemical Property:

Appearance/Colour:white powder or chunks
Vapor Pressure:3.69E-11mmHg at 25°C
Melting Point:116-120oC
Boiling Point:495.3 °C at 760 mmHg
PKA:4.51±0.10(Predicted)
Flash Point:253.3 °C
PSA：118.72000
Density:1.22 g/cm³
LogP:1.32100
Storage Temp.:Store at RT.
XLogP3:-0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:245.11374665
Heavy Atom Count:17
Complexity:303

Purity/Quality:

97% ^*data from raw suppliers

Boc-L-Glu-NH2 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CCC(=O)[O-])C(=O)N
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CCC(=O)[O-])C(=O)N

Technology Process of 4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate

There total 1 articles about 4-{[tert-Butoxy(hydroxy)methylidene]amino}-5-hydroxy-5-iminopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13574-13-5
Boc-Glu(OBzl)-OH

: 541-41-3
chloroformic acid ethyl ester

: 18800-74-3
(4S)-4-(N-tert-butoxycarbonylamino)-4-(carbamoyl)butanoic acid

Guidance literature:: With ammonia; triethylamine; In tetrahydrofuran; methanol; water;

Reference yield: 71.0%

: 18800-74-3
(4S)-4-(N-tert-butoxycarbonylamino)-4-(carbamoyl)butanoic acid

: 7693-46-1
4-Nitrophenyl chloroformate

: N-Boc-L-γ-isoglutaminyl p-nitrophenyl ester

Guidance literature:: With dmap; triethylamine; In ethyl acetate; at 25 ℃; for 3h;
DOI:10.1016/S0968-0896(02)00165-7

Reference yield: 54.0%

: 93493-95-9
2-{[(trifluoromethyl)sulfonyl]oxy}cyclohex-1-enecarboxylic acid methyl ester

: 18800-74-3
(4S)-4-(N-tert-butoxycarbonylamino)-4-(carbamoyl)butanoic acid

: 1051923-04-6
C₁₈H₂₈N₂O₇

Guidance literature:: With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; caesium carbonate; In 1,4-dioxane; at 80 ℃; for 4h;
DOI:10.1016/j.tetlet.2008.05.148