3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one

Base Information

Chemical Name:3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one
CAS No.:243666-35-5
Molecular Formula:C₁₆H₁₃ClO₂
Molecular Weight:272.731
Hs Code.:
DSSTox Substance ID:DTXSID001177597
Nikkaji Number:J1.173.255K

Synonyms:DTXSID001177597;243666-35-5;3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one

Suppliers and Price of 3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:268.109944368
Heavy Atom Count:20
Complexity:346

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)OC(=O)CC2C3=CC=C(C=C3)OC

Technology Process of 3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one

There total 2 articles about 3,4-Dihydro-4-(4-methoxyphenyl)-6-methyl-2H-1-benzopyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1679-18-1
4-Chlorophenylboronic acid

: 92-48-8
6-methylcoumarin

: 243666-35-5
(R)-6-methyl-4-(4-chlorophenyl)chroman-2-one

Guidance literature:: With bis(ethylene)rhodium acetylacetonate; (R)-segphos; In 1,4-dioxane; water; at 60 ℃; for 10h;
DOI:10.1021/ol0507367

Reference yield:

: 1679-18-1
4-Chlorophenylboronic acid

: 92-48-8
6-methylcoumarin

: 243666-35-5
(R)-6-methyl-4-(4-chlorophenyl)chroman-2-one

: (S)-4-(4-chlorophenyl)-6-methylchroman-2-one

: C₁₆H₁₁ClO₂

Guidance literature:: With palladium(II) trifluoroacetate; C₁₈H₁₉N₃O; In 1,2-dichloro-ethane; Overall yield = 55 percent; Overall yield = 30 mg; enantioselective reaction; Schlenk technique; Inert atmosphere; Heating;
DOI:10.1021/acs.orglett.1c04366