(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

Base Information

Chemical Name:(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol
CAS No.:291533-26-1
Molecular Formula:C₁₄H₂₁NO₃
Molecular Weight:251.326
Hs Code.:

Synonyms:(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

Chemical Property:

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Technology Process of (R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

There total 2 articles about (R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 77184-10-2
1,1-dimethylethyl methyl(2-phenyl-2-oxoethyl)carbamate

: 291533-26-1
(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

Guidance literature:: With trans-RuCl₂[(R)-xylbinap][(R)-daipen]; potassium tert-butylate; hydrogen; In isopropyl alcohol; tert-butyl alcohol; at 25 ℃; for 7h; under 6080.41 Torr;
DOI:10.1021/ja001098k

Reference yield:

: 77184-10-2
1,1-dimethylethyl methyl(2-phenyl-2-oxoethyl)carbamate

: 127239-58-1
(+)-(S)-2-{t-butoxycarbonyl(methyl)amino}-1-phenylethanol

: 291533-26-1
(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

Guidance literature:: With potassium hydroxide; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; (1S,2R)-1-amino-2-indanol; In isopropyl alcohol; at 20 ℃; for 2h; Title compound not separated from byproducts;
DOI:10.1055/s-1999-2906