Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid tert-butyl ester

Base Information

Chemical Name:Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid tert-butyl ester
CAS No.:77184-10-2
Molecular Formula:C₁₄H₁₉NO₃
Molecular Weight:249.31
Hs Code.:
DSSTox Substance ID:DTXSID701188759
Nikkaji Number:J1.198.666H

Synonyms:138371-45-6;METHYL-(2-OXO-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER;tert-Butyl methyl(2-oxo-2-phenylethyl)carbamate;77184-10-2;tert-butyl N-methyl-N-phenacylcarbamate;tert-butyl N-methyl-N-(2-oxo-2-phenylethyl)carbamate;SCHEMBL15973703;WFKSNAFHIMNMLV-UHFFFAOYSA-N;DTXSID701188759;MFCD11506029;AKOS024260994;SB33240;Methylphenacylcarbamic acid tert-butyl ester;CS-0346441;FT-0751953;EN300-797911;Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid t-butyl ester;Methyl-(2-oxo-2-phenylethyl)carbamic acid tert-butyl ester;1,1-Dimethylethyl N-methyl-N-(2-oxo-2-phenylethyl)carbamate

Suppliers and Price of Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid tert-butyl ester

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:301

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(C)CC(=O)C1=CC=CC=C1

Technology Process of Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid tert-butyl ester

There total 13 articles about Methyl-(2-oxo-2-phenyl-ethyl)-carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 7541-17-5
tert-butyl N,N-dimethylcarbamate

: 98-88-4
benzoyl chloride

: 77184-10-2
1,1-dimethylethyl methyl(2-phenyl-2-oxoethyl)carbamate

Guidance literature:: tert-butyl N,N-dimethylcarbamate; With sec.-butyllithium; (-)-sparteine; In tetrahydrofuran; at -78 ℃; for 1h;

With lithium chloride; In tetrahydrofuran; at -55 ℃; for 1h;

benzoyl chloride; In tetrahydrofuran; at -50 - 20 ℃;
DOI:10.1016/S0040-4020(02)01526-0

Reference yield: 98.0%

: 77184-09-9
N-(β-Hydroxyphenaethyl)-N-methyl-carbaminsaeure-(t-butyl)ester

: 77184-10-2
1,1-dimethylethyl methyl(2-phenyl-2-oxoethyl)carbamate

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 ℃; for 4.5h;
DOI:10.1002/hlca.200790144

Reference yield: 89.0%

: 66324-10-5
tert-butyldimethyl(1-phenylvinyloxy)silane

: 1-((tert-butoxycarbonyl)(methyl)amino)-2,4,6-trimethylpyridin-1-ium tetrafluoroborate

: 77184-10-2
1,1-dimethylethyl methyl(2-phenyl-2-oxoethyl)carbamate

Guidance literature:: With fac-tris[2-phenylpyridinato-C²,N]iridium(III); In acetonitrile; at 20 - 22 ℃; for 1h; chemoselective reaction; Inert atmosphere; Irradiation;
DOI:10.1021/acs.joc.9b02073