4-carboxy-3,5-dihydroxyphenylacetic acid

Base Information

• Chemical Name: 4-carboxy-3,5-dihydroxyphenylacetic acid
• CAS No.: 124792-99-0
• Molecular Formula: C₉H₈O₆
• Molecular Weight: 212.159
• Mol file: 124792-99-0.mol

Synonyms:4-carboxy-3,5-dihydroxyphenylacetic acid

Chemical Property of 4-carboxy-3,5-dihydroxyphenylacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-carboxy-3,5-dihydroxyphenylacetic acid

There total 1 articles about 4-carboxy-3,5-dihydroxyphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.2%

dimethyl 2,4-dihydroxy-6-(2-methoxy-2-oxoethyl)benzene-1,3-dicarboxylate (6512-25-0) → 4-carboxy-3,5-dihydroxyphenylacetic acid (124792-99-0)

Guidance literature:

With sulfuric acid; at 65 ℃;

Reference yield: 83.2%

4-carboxy-3,5-dihydroxyphenylacetic acid (124792-99-0) + methyl iodide (74-88-4) → 4-carboxy-3,5-dimethoxyphenylacetic acid dimethyl ester (76008-80-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; Ambient temperature;

Reference yield: 83.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 4-carboxy-3,5-dihydroxyphenylacetic acid (124792-99-0) → methyl 3,5-dihydroxy-4-methoxycarbonylphenylacetate (124793-00-6)

Guidance literature:

In methanol; diethyl ether; for 0.166667h; Ambient temperature;

upstream raw materials:

dimethyl 2,4-dihydroxy-6-(2-methoxy-2-oxoethyl)benzene-1,3-dicarboxylate

Downstream raw materials:

methyl 3,5-dihydroxy-4-methoxycarbonylphenylacetate

4-carboxy-3,5-dimethoxyphenylacetic acid dimethyl ester

methyl 2-acetyl-3,5-dihydroxy-4-methoxycarbonylphenylacetate

methyl 2-crotonyl-3,5-dihydroxy-4-methoxycarbonylphenylacetate

Refernces