4,4'-Bis(ethoxycarbonly)-2,2'-bipyridine

Base Information

• Chemical Name: 4,4'-Bis(ethoxycarbonly)-2,2'-bipyridine
• CAS No.: 1762-42-1
• Molecular Formula: C16H16N2O4
• Molecular Weight: 300.314
• Hs Code.: 2933399090
• Mol file: 1762-42-1.mol

Synonyms:2,2'-Bipyridinyl-4,4'-dicarboxylic acid diethyl ester;4,4'-Dicarbethoxy-2,2'-bipyridine;4,4'-Dicarboethoxy-2,2'-dipyridyl;Diethyl 2,2'-bipyridine-4,4'-dicarboxylate;Diethyl 2,2'-diisonicotinate;[2,2'-Bipyridine]-4,4'-dicarboxylic acid, diethylester (9CI);2,2'-Biisonicotinicacid, diethyl ester (6CI,7CI,8CI);

Chemical Property of 4,4'-Bis(ethoxycarbonly)-2,2'-bipyridine

Chemical Property:

• Melting Point: 160-161 °C(Solv: ethanol (64-17-5))
• Boiling Point: 460.624 °C at 760 mmHg
• PKA: 1.94±0.30(Predicted)
• Flash Point: 232.377 °C
• PSA: 78.38000
• Density: 1.201 g/cm³
• LogP: 2.49700
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98.0%Min ^*data from raw suppliers

4,4''-Bis(ethoxycarbonyl)-2,2’-bipyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-Bis(ethoxycarbonly)-2,2'-bipyridine

There total 11 articles about 4,4'-Bis(ethoxycarbonly)-2,2'-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethanol (64-17-5) + 2,2'-Bipyridine-4,4'-dicarboxylic acid (6813-38-3) → 4,4'-bis(ethoxycarbonyl)-2,2'-bipyridine (1762-42-1)

Guidance literature:

With sulfuric acid; for 18h; Heating;

DOI:10.1021/jp9710805

Reference yield: 90.0%

ethanol (64-17-5) + 2,2'-bipyridyl-4,4'-dicarboxylic acid chloride (72460-28-7) → 4,4'-bis(ethoxycarbonyl)-2,2'-bipyridine (1762-42-1)

Guidance literature:

With triethylamine; at 0 - 20 ℃; for 5h; Reflux;

DOI:10.1016/j.poly.2013.04.011

Reference yield: 90.0%

→ 4,4'-bis(ethoxycarbonyl)-2,2'-bipyridine (1762-42-1)

Guidance literature:

With sulfuric acid; for 24h; Reflux;

With sodium hydroxide; In water; at 0 ℃;

upstream raw materials:

ethanol

2,2'-Bipyridine-4,4'-dicarboxylic acid

2,2'-bipyridyl-4,4'-dicarboxylic acid chloride

isonicotinic acid ethylester

Downstream raw materials:

4,4'-bis(ethoxycarbonyl)-2,2'-bipyridine-N,N'-dioxide

[(4,4′-diethoxycarbonyl-2,2′-bipyridine)PtPh₂]

Refernces

• 1、 Günyar, Alev,Betz, Daniel,Drees, Markus,Herdtweck, Eberhardt,Kühn, Fritz E.. "Highly soluble dichloro, dibromo and dimethyl dioxomolybdenum(VI)- bipyridine complexes as catalysts for the epoxidation of olefins". . p. 117 - 124. Retrieved 2010.
• 2、 Nguyen, The-Duy,Lin, Chun-Han,Wu, Chun-Guey. "Effect of the CF3 Substituents on the Charge-Transfer Kinetics of High-Efficiency Cyclometalated Ruthenium Sensitizers". . p. 252 - 260. Retrieved 2017.
• 3、 Brown, Asha,Mennie, Katrina M.,Mason, Owen,White, Nicholas G.,Beer, Paul D.. "Copper(II)-directed synthesis of neutral heteroditopic [2]rotaxane ion-pair host systems incorporating hydrogen and halogen bonding anion binding cavities". . p. 13376 - 13385. Retrieved 2017.
• 4、 Ardo, Shane,Sun, Yali,Staniszewski, Aaron,Castellano, Felix N.,Meyer, Gerald J.. "Stark effects after excited-state interfacial electron transfer at sensitized TiO2 nanocrystallites". . p. 6696 - 6709. Retrieved 2010.
• 5、 Sahin, Cigdem,Goren, Aysen,Demir, Serkan,Cavus, Muhammet Serdar. "New amide based iridium(III) complexes: Synthesis, characterization, photoluminescence and DFT/TD-DFT studies". . p. 2979 - 2988. Retrieved 2018.
• 6、 Carre?o, Alexander,Páez-Hernández, Dayán,Zú?iga, César,Ramírez-Osorio, Angélica,Nevermann, Jan,Rivera-Zaldívar, María Macarena,Otero, Carolina,Fuentes, Juan A.. "Prototypical cis-ruthenium(II) complexes present differential fluorescent staining in walled-cell models (yeasts)". . p. 1629 - 1637. Retrieved 2019.
• 7、 Turlington, Michael D.,Troian-Gautier, Ludovic,Sampaio, Renato N.,Beauvilliers, Evan E.,Meyer, Gerald J.. "Control of Excited-State Supramolecular Assembly Leading to Halide Photorelease". . p. 3316 - 3328. Retrieved 2019/05/25.