Cinnolin-3(2H)-one

Base Information

• Chemical Name: Cinnolin-3(2H)-one
• CAS No.: 31777-46-5
• Molecular Formula: C8H6N2O
• Molecular Weight: 146.148
• Hs Code.: 2933990090
• Mol file: 31777-46-5.mol

Synonyms:3-Cinnolinol;NSC 35117;

Chemical Property of Cinnolin-3(2H)-one

Chemical Property:

• Vapor Pressure: 0.175mmHg at 25°C
• Melting Point: 201-203 °C
• Refractive Index: 1.666
• Boiling Point: 205.4 °C at 760 mmHg
• PKA: 9.47±0.20(Predicted)
• Flash Point: 78 °C
• PSA: 45.75000
• Density: 1.31 g/cm³
• LogP: 0.92310
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cinnolin-3(2H)-one 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cinnolin-3(2H)-one

There total 6 articles about Cinnolin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1,4-Dihydro-3(2H)-cinnolinone (55116-04-6) → cinnolin-3(2H)-one (31777-46-5)

Guidance literature:

With lead(IV) acetate;

Reference yield: 54.0%

1-amino-1,3-dihydro-2H-indol-2-one (36149-75-4) → cinnolin-3(2H)-one (31777-46-5)

Guidance literature:

With lead(IV) acetate; In dichloromethane; for 5h; Mechanism; Ambient temperature; also with 15N-labelled compounds;

Reference yield:

→ cinnolin-3(2H)-one (31777-46-5)

Guidance literature:

With tin(ll) chloride; Behandeln des Reaktionsprodukts mit verd. Salzsaeure;

upstream raw materials:

2-amino-DL-mandelic acid

1,4-Dihydro-3(2H)-cinnolinone

1-amino-1,3-dihydro-2H-indol-2-one

Downstream raw materials:

3-p-tolylsulfanylcinnoline

3-p-tolylsulfinylcinnoline

2-oxoindole

3-chlorocinnoline

Refernces

• 1、 -. "Pesticides". . . Retrieved 2008/06/13.
• 2、 Williams, Michael T.. "Rearrangements of N-Nitrenes: a 15N- Labelling Study of the Mechanism of the Conversion of 1-Aminoindol-2-one to Cinnolin-3(2H)-one". . p. 1185 - 1194. Retrieved 2007/10/02.