4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester

Base Information

• Chemical Name: 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester
• CAS No.: 153037-21-9
• Molecular Formula: C₁₉H₂₈N₂O₆
• Molecular Weight: 380.441

Synonyms:4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester

Chemical Property of 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester

There total 2 articles about 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester (153037-21-9)

Guidance literature:

With 4-methyl-morpholine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 18h;

Reference yield: 96.0%

5-tert-butyl N-benzyloxycarbonyl-L-glutamate (3886-08-6) + N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) → 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester (153037-21-9)

Guidance literature:

5-tert-butyl N-benzyloxycarbonyl-L-glutamate; With 4-methyl-morpholine; isobutyl chloroformate; In dichloromethane; at -15 ℃; for 0.5h;

N,O-dimethylhydroxylamine*hydrochloride; In dichloromethane; at -15 - 20 ℃; for 2h;

DOI:10.1016/S0040-4020(00)00165-4

Reference yield: 99.0%

4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester (153037-21-9) → 4(S)-benzyloxycarbonylamino-5-oxo-pentanoic acid tert-butyl ester (92506-78-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at -40 ℃; for 2.66667h;

DOI:10.1016/S0040-4020(00)00165-4

upstream raw materials:

5-tert-butyl N-benzyloxycarbonyl-L-glutamate

N,O-dimethylhydroxylamine*hydrochloride

Downstream raw materials:

4(S)-benzyloxycarbonylamino-5-oxo-pentanoic acid tert-butyl ester

1-(S)-(N-carbobenzyloxy)amino-1,2,3,4,6,7,12,12b-(R)-octahydroindolo<2,3-a>quinolizidin-4-one

1(R)-4'(S)-benzyloxycarbonylamino-4'-(1,2,3,4-tetrahydro-1H-β-carbolin-1-yl)butyric acid tert-butyl ester

1-(S)-(N-benzyloxycarbonyl)-amino-1,2,3,4,6,7,12,12b-(R)-octahydroindolo<2,3-a>quinolizidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 153037-21-9 4(S)-benzyloxycarbonylamino-4-(methoxymethylcarbamoyl)butyric acid tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send