1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Base Information

• Chemical Name: 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
• CAS No.: 91509-71-6
• Molecular Formula: C₁₂H₁₂Cl₂N₄O₂
• Molecular Weight: 315.159

Synonyms:1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Chemical Property of 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Chemical Property:

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Technology Process of 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

There total 3 articles about 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trimethylsilyl)acetamide (BSA) + 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone (58905-16-1) → 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol (91509-71-6)

Guidance literature:

With hydrogenchloride; n-butyllithium; sodium hydrogencarbonate; In tetrahydrofuran; hexane; water;

Reference yield:

1-cyano-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol (91509-69-2) → 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol (91509-71-6)

Guidance literature:

In methanol; hexane; dichloromethane; sulfuric acid; water; acetone;

Reference yield:

3-(2,4-dichlorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butyrimidic acid,ethyl ester dihydrochloride → 1-Carbamoyl-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol (91509-71-6)

Guidance literature:

In 1,2-dichloro-benzene; acetone;

upstream raw materials:

1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone

1-cyano-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

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