(S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

Base Information

Chemical Name:(S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal
CAS No.:1404099-76-8
Molecular Formula:C₂₇H₂₄ClNO₃
Molecular Weight:445.945
Hs Code.:

Synonyms:(S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

Suppliers and Price of (S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

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Chemical Property of (S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

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Technology Process of (S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

There total 2 articles about (S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26960-68-9
1-benzyl-5-chloroisatin

: 70925-46-1,56161-69-4
(2E)-2-methyl-5-phenyl-2-pentenal

: 1404099-76-8
(S,E)-4-((R)-1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

: (E)-4-(1-benzyl-5-chloro-3-hydroxy-2-oxoindolin-3-yl)-2-methyl-5-phenylpent-2-enal

Guidance literature:: With (-)-(S)-α,α-diphenylpyrrolidine-2-methanol methyl(diphenyl)silyl ether; 2,6-bis(trifluoromethyl)benzoic acid; In ethanol; acetonitrile; at 25 ℃; for 40h; Overall yield = 69 %; enantioselective reaction;
DOI:10.1021/ol302711w