Technology Process of 1-(2,3-dimethoxy-5-methylphenyl)-2-methyl-propan-1-one
There total 8 articles about 1-(2,3-dimethoxy-5-methylphenyl)-2-methyl-propan-1-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
silica gel; pyridinium chlorochromate;
In
dichloromethane;
at 20 ℃;
for 2h;
DOI:10.1016/j.tet.2006.01.021
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 95 percent / K2CO3 / acetone / 6 h / Heating
2.1: 90 percent / 24 h / 180 °C
3.1: 95 percent / KOH / methanol / 10 h / Heating
4.1: 96 percent / sodium hydroxyde / H2O / 1 h / Heating
5.1: NaHCO3; ozone / methanol; CH2Cl2 / 0.22 h / -70 °C
5.2: 80 percent / dimethyl sulfide / methanol; CH2Cl2 / 8 h / 20 °C
6.1: Mg; iodine / diethyl ether
6.2: 88 percent / diethyl ether / 3 h / 20 °C
7.1: 96 percent / PCC; silica gel / CH2Cl2 / 2 h / 20 °C
With
potassium hydroxide; sodium hydroxide; iodine; silica gel; sodium hydrogencarbonate; potassium carbonate; ozone; magnesium; pyridinium chlorochromate;
In
methanol; diethyl ether; dichloromethane; water; acetone;
2.1: Claisen rearrangement / 6.2: Grignard reaction;
DOI:10.1016/j.tet.2006.01.021
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Mg; iodine / diethyl ether
1.2: 88 percent / diethyl ether / 3 h / 20 °C
2.1: 96 percent / PCC; silica gel / CH2Cl2 / 2 h / 20 °C
With
iodine; silica gel; magnesium; pyridinium chlorochromate;
In
diethyl ether; dichloromethane;
1.2: Grignard reaction;
DOI:10.1016/j.tet.2006.01.021
