2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester

Base Information

Chemical Name:2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester
CAS No.:1202357-66-1
Molecular Formula:C₁₁H₁₁ClN₄O₂S
Molecular Weight:298.753
Hs Code.:
Mol file:1202357-66-1.mol

Synonyms:ethyl 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxylate

Suppliers and Price of 2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester 95%
5g
$ 1488.00

A1 Biochem Labs
2-(6-Chloro-2-methyl-pyrimidin-4-ylamino)-thiazole-5-carboxylicacidethylester 95%
5 g
$ 850.00

Total 4 raw suppliers

Chemical Property of 2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester

There total 1 articles about 2-(6-Chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1780-26-3
2,4-dichloro-2-methylpyrimidine

: 32955-21-8
2-amino-thiazole-5-carboxylic acid ethyl ester

: 1202357-66-1
ethyl 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxylate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 72h; Inert atmosphere;

Reference yield: 89.0%

: 887583-71-3
1-[2-(tert-butyldiphenylsilanyloxy)ethyl]piperazine

: 1202357-66-1
ethyl 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxylate

: C₃₃H₄₂N₆O₃SSi

Guidance literature:: In 1,4-dioxane; at 103 ℃;
DOI:10.1016/j.bmcl.2018.01.011

Reference yield:

: 1202357-66-1
ethyl 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxylate

: 302964-08-5
2-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / methanol; water / 16 h / 20 °C

2: N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C / Inert atmosphere

With water; N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; water; acetonitrile;