tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Base Information

Chemical Name:tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside
CAS No.:565462-86-4
Molecular Formula:C₅₄H₅₈O₉S
Molecular Weight:883.115
Hs Code.:

Synonyms:tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Suppliers and Price of tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

There total 6 articles about tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 2746-25-0
p-Methoxybenzyl bromide

: 565462-98-8
tetrahydropyran-2-yl 6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

: 565462-86-4
tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00072-6

Reference yield:

: 137886-82-9
2,3,4,6-Tetra-O-acetyl-5-thio-α-D-glucopyranose

: 565462-86-4
tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / p-TsOH / CH₂Cl₂ / 1.5 h / 0 °C

2: 82 percent / NaOMe / methanol / 3.5 h / 20 °C

3: 80 percent / 4-(dimethylamino)pyridine; pyridine / 24 h / 20 °C

4: 56 percent / NaH / dimethylformamide / 20 °C

With pyridine; dmap; sodium methylate; sodium hydride; toluene-4-sulfonic acid; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2005.05.028

Reference yield:

: 453525-11-6
tetrahydropyran-2-yl 2,3,4,6-tetra-O-acetyl-5-deoxy-5-thio-α-D-glucopyranoside

: 565462-86-4
tetrahydropyran-2-yl 2,3,4-[tris-O-(4-methoxyphenyl)methyl]-6-O-triphenylmethyl-5-deoxy-5-thio-α-D-glucopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / NaOMe / methanol / 3.5 h / 20 °C

2: 80 percent / 4-(dimethylamino)pyridine; pyridine / 24 h / 20 °C

3: 56 percent / NaH / dimethylformamide / 20 °C

With pyridine; dmap; sodium methylate; sodium hydride; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2005.05.028