2-((2-Chloro-4-nitrophenoxy)methyl)pyridine

Base Information

Chemical Name:2-((2-Chloro-4-nitrophenoxy)methyl)pyridine
CAS No.:179687-79-7
Molecular Formula:C12H9ClN2O3
Molecular Weight:264.668
Hs Code.:2933399090
European Community (EC) Number:605-865-3
UNII:789FX466M2
DSSTox Substance ID:DTXSID70589630
Wikidata:Q72455906
Mol file:179687-79-7.mol

Synonyms:179687-79-7;2-((2-Chloro-4-nitrophenoxy)methyl)pyridine;2-[(2-CHLORO-4-NITROPHENOXY)METHYL]PYRIDINE;Pyridine, 2-[(2-chloro-4-nitrophenoxy)methyl]-;3-chloro-4-(2-pyridinylmethoxy)-1-nitrobenzene;789FX466M2;3-Chloro-4-(2-pyridylmethyloxy)nitrobenzene;2-(2-Chloro-4-nitrophenoxy)methylpyridine;3-Chloro-4-(2-pyridylmethoxy)nitrobenzene;EC 605-865-3;SCHEMBL215759;UNII-789FX466M2;DTXSID70589630;GWYKHOLLVPAQFF-UHFFFAOYSA-N;BCP25982;CS-M0296;MFCD09380073;AKOS015914451;DS-14799;3-chloro-4-(2-pyridylmethoxyl)-nitrobenzene;NS00007146;2-(2-Chloro-4-nitro-phenoxymethyl)-pyridine;2-[(2-chloranyl-4-nitro-phenoxy)methyl]pyridine;2-(2-CHLORO-4-NITROPHENOXYMETHYL)PYRIDINE;A812474;Z193645932;3-Chloro-4-(2-pyridinylmethoxy)-1-nitrobenzene 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine

Suppliers and Price of 2-((2-Chloro-4-nitrophenoxy)methyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-((2-Chloro-4-nitrophenoxy)methyl)pyridine 95+%
10g
$ 495.00

Crysdot
2-((2-Chloro-4-nitrophenoxy)methyl)pyridine 95+%
5g
$ 297.00

ChemScene
2-((2-chloro-4-nitrophenoxy)methyl)pyridine
250mg
$ 104.00

Chemenu
2-((2-Chloro-4-nitrophenoxy)methyl)pyridine 95%
10g
$ 468.00

Chemenu
2-((2-Chloro-4-nitrophenoxy)methyl)pyridine 95%
1g
$ 102.00

Chemenu
2-((2-Chloro-4-nitrophenoxy)methyl)pyridine 95%
5g
$ 281.00

Biosynth Carbosynth
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
1 g
$ 260.00

Biosynth Carbosynth
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
500 mg
$ 170.00

Biosynth Carbosynth
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
2 g
$ 340.00

Biosynth Carbosynth
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
10 g
$ 910.00

Total 44 raw suppliers

Chemical Property of 2-((2-Chloro-4-nitrophenoxy)methyl)pyridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:125-129oC
Refractive Index:1.618
Boiling Point:414.736 °C at 760 mmHg
Flash Point:204.625 °C
PSA：67.94000
Density:1.385 g/cm³
LogP:3.74540
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:264.0301698
Heavy Atom Count:18
Complexity:285

Purity/Quality:

99% ^*data from raw suppliers

2-((2-Chloro-4-nitrophenoxy)methyl)pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)COC2=C(C=C(C=C2)[N+](=O)[O-])Cl
Uses 3-Chloro-4-(2-pyridylmethyloxy)nitrobenzene was used to synthesize aniline ''headgroups'' and incorporat them into an alkynyl thienopyrimidine series of EGFR and ErbB-?2 inhibitors.

Technology Process of 2-((2-Chloro-4-nitrophenoxy)methyl)pyridine

There total 8 articles about 2-((2-Chloro-4-nitrophenoxy)methyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 350-30-1
3-chloro-4-fluoronitrobenzene

: 179687-79-7
2-((2-chloro-4-nitrophenoxy)methyl)pyridine

Guidance literature:: 2-Hydroxymethylpyridine; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 0 ℃; for 0.25h;

3-chloro-4-fluoronitrobenzene; for 36h;

Reference yield: 98.0%

: 619-08-9
2-chloro-4-nitrophenol

: 6959-47-3
2-chloromethylpyridine hydrochloride

: 179687-79-7
2-((2-chloro-4-nitrophenoxy)methyl)pyridine

Guidance literature:: 2-chloromethylpyridine hydrochloride; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

2-chloro-4-nitrophenol; With potassium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 12h;
DOI:10.1016/j.bmc.2013.03.053

Reference yield: 97.0%

: 4377-33-7
2-chloromethylpyridine

: 619-08-9
2-chloro-4-nitrophenol

: 179687-79-7
2-((2-chloro-4-nitrophenoxy)methyl)pyridine

Guidance literature:: 2-chloromethylpyridine; With potassium carbonate; In N,N-dimethyl-formamide; for 0.5h;

2-chloro-4-nitrophenol; With potassium iodide; In N,N-dimethyl-formamide; at 60 ℃;
DOI:10.1021/acs.jmedchem.0c00870