O-(cyclopropylmethyl)hydroxylamine

Base Information

• Chemical Name: O-(cyclopropylmethyl)hydroxylamine
• CAS No.: 75647-90-4
• Molecular Formula: C4H9NO
• Molecular Weight: 87.1216
• Hs Code.: 2922199090
• European Community (EC) Number: 819-319-9
• DSSTox Substance ID: DTXSID70457845
• Nikkaji Number: J2.227.383C
• Wikidata: Q72460967
• Mol file: 75647-90-4.mol

Synonyms:O-(cyclopropylmethyl)hydroxylamine;75647-90-4;O-Cyclopropylmethylhydroxylamine;Cyclopropyl methoxylamine;HYDROXYLAMINE, O-(CYCLOPROPYLMETHYL)-;O-cyclopropylmethyl-hydroxylamine;O-cyclopropylmethylhydroxyamine;[(Aminooxy)methyl]cyclopropane;DTXSID70457845;YHNRUSMOYCDMJS-UHFFFAOYSA-N;AKOS005207019;AM90383;BB 0262341;FT-0601101;EN300-221347;A838475;J-523805

Chemical Property of O-(cyclopropylmethyl)hydroxylamine

Chemical Property:

• Vapor Pressure: 4.37mmHg at 25°C
• Boiling Point: 147.7 °C at 760 mmHg
• Flash Point: 54.5 °C
• PSA: 35.25000
• Density: 1.032 g/cm³
• LogP: 0.98700
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 87.068413911
• Heavy Atom Count: 6
• Complexity: 42.8

Purity/Quality:

99% ^*data from raw suppliers

CyclopropylMethoxylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1CON

Technology Process of O-(cyclopropylmethyl)hydroxylamine

There total 3 articles about O-(cyclopropylmethyl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

→ O-cyclopropylmethyl-hydroxylamine (75647-90-4)

Guidance literature:

Reference yield:

2-(cyclopropylmethoxy)isoindoline-1,3-dione (113211-15-7) → O-cyclopropylmethyl-hydroxylamine (75647-90-4)

Guidance literature:

With N,N`-dimethylethylenediamine; In ethanol; at 20 ℃; for 15h;

DOI:10.1016/j.bmcl.2007.10.090

Reference yield:

Cyclopropylmethanol (2516-33-8) → O-cyclopropylmethyl-hydroxylamine (75647-90-4)

Guidance literature:

Cyclopropylmethanol; With sodium hydride; In diethyl ether; at -15 ℃;

With mesitylenesulfonylhydroxylamine; In diethyl ether; at -15 - 0 ℃;

DOI:10.1021/jf801901h

upstream raw materials:

2-(cyclopropylmethoxy)isoindoline-1,3-dione

Cyclopropylmethanol

Downstream raw materials:

N-cyclopropylmethoxy-3,4,5-trifluoro-2-(4-iodo-2-methyl-phenylamino)-benzamide

C₁₄H₁₆ClF₃N₂O₃S

N-[4-chloro-2-(1-cyclopropylmethoxyiminoethyl)phenyl]trifluoromethanesulfonamide

7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide

Refernces

• 1、 -. "PROCESS FOR THE PREPARATION OF QUINOLONE BASED COMPOUNDS". Paragraph 0241; 0244; 0275; 0277. . Retrieved 2019/12/06.
• 2、 -. "N-ALKOXYAMIDES OF 6-(TRISUBSTITUTED PHENYL)-4-AMINOPICOLINATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS". Page/Page column 6. . Retrieved 2010/09/07.