7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide

Base Information

Chemical Name:7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide
CAS No.:1193487-78-3
Molecular Formula:C₂₀H₂₁BrFN₃O₃
Molecular Weight:450.307
Hs Code.:

Synonyms:7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide

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Chemical Property of 7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide

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Technology Process of 7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide

There total 1 articles about 7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.7%

: 1193487-77-2
7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid

: 75647-90-4
O-cyclopropylmethyl-hydroxylamine

: 1193487-78-3
7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide

Guidance literature:: 7-(4-bromo-2-methyl-phenylamino)-6-fluoro-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

O-cyclopropylmethyl-hydroxylamine; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;