methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

Base Information

Chemical Name:methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate
CAS No.:549494-31-7
Molecular Formula:C₁₉H₂₁ClO₆S
Molecular Weight:412.891
Hs Code.:

Synonyms:methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

Chemical Property:

Boiling Point:571.2±50.0 °C(Predicted)
Density:1.303±0.06 g/cm3(Predicted)

Purity/Quality:

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Technology Process of methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

There total 5 articles about methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 549494-35-1
methyl 2-chloro-3-(4-[2-(4-hydroxyphenoxy)ethyl]phenyl)propanoate

: 124-63-0
methanesulfonyl chloride

: 549494-31-7
methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

Guidance literature:: With triethylamine; In dichloromethane; at -20 - 20 ℃; for 2h;

Reference yield:

: 549494-33-9
methyl 2-chloro-3-[4-(2-hydroxyethyl)phenyl]propanoate

: 549494-31-7
methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene

2: dimethylsulfide; boron trifluoride diethyl etherate / dichloromethane / 48 h / 20 °C

3: triethylamine / dichloromethane / 2 h / -20 - 20 °C

With dimethylsulfide; di-isopropyl azodicarboxylate; boron trifluoride diethyl etherate; triethylamine; triphenylphosphine; In dichloromethane; toluene;

Reference yield:

: 549494-34-0
methyl 3-(4-(2-[4-(benzyloxy)phenoxy]ethyl)phenyl)-2-chloropropanoate

: 549494-31-7
methyl 2-chloro-3-[4-(2-(4-[(methylsulfonyl)oxy]phenoxy)ethyl)phenyl]propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylsulfide; boron trifluoride diethyl etherate / dichloromethane / 48 h / 20 °C

2: triethylamine / dichloromethane / 2 h / -20 - 20 °C

With dimethylsulfide; boron trifluoride diethyl etherate; triethylamine; In dichloromethane;