2,6-Bis[1-(2-ethylphenylimino)ethyl]pyridine

Base Information

• Chemical Name: 2,6-Bis[1-(2-ethylphenylimino)ethyl]pyridine
• CAS No.: 210537-33-0
• Molecular Formula: C₂₅H₂₇N₃
• Molecular Weight: 369.509
• DSSTox Substance ID: DTXSID001191896
• Nikkaji Number: J1.519.345J
• Mol file: 210537-33-0.mol

Synonyms:2,6-bis[1-(2-ethylphenylimino)ethyl]pyridine;SCHEMBL5144785;FUPONKLSOMQBNK-UHFFFAOYSA-N;DTXSID001191896;n,n'-(2,6-pyridinediyldiethylidyne)bis[2-ethylbenzenamine];210537-33-0

Chemical Property of 2,6-Bis[1-(2-ethylphenylimino)ethyl]pyridine

Chemical Property:

• XLogP3: 6.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 369.220497874
• Heavy Atom Count: 28
• Complexity: 492

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC1=CC=CC=C1N=C(C)C2=NC(=CC=C2)C(=NC3=CC=CC=C3CC)C

Technology Process of 2,6-Bis[1-(2-ethylphenylimino)ethyl]pyridine

There total 1 articles about 2,6-Bis[1-(2-ethylphenylimino)ethyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

2,6-Diacetylpyridine (1129-30-2) + ortho-ethylaniline (578-54-1) → 2,6-bis[1-(2-ethylphenylimino)ethyl]-pyridine (210537-33-0)

Guidance literature:

With formic acid; In methanol; at 20 ℃; for 15h;

DOI:10.1016/S0022-328X(03)00670-3

Reference yield: 99.0%

iron(II) chloride + 2,6-bis[1-(2-ethylphenylimino)ethyl]-pyridine (210537-33-0) → [FeCl2(2,6-bis[1-(2-ethylphenylimino)ethyl]-pyridine)] (210537-36-3)

Guidance literature:

In tetrahydrofuran; (Ar); dry FeCl2 in THF stirred, a soln. of ligand added slowly at room temp. dropwise, stirred for 1 h; pentane added, the solid filtered, dried (Ar);

DOI:10.1016/S0022-328X(03)00670-3

Reference yield: 99.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + cobalt(II) chloride hexahydrate + 2,6-bis[1-(2-ethylphenylimino)ethyl]-pyridine (210537-33-0) → 2,6-bis[1-(2-ethylphenylimino)ethyl]pyridinecobalt(II) chloride-tetrahydrofuran (1/1) (677352-44-2)

Guidance literature:

stirring a slight excess of the ligand with CoCl2*6H2O in THF for at least 1 day; adding pentane to soln.; filtration; heating under vac. at 40 °C;elem. anal.;

DOI:10.1021/om030210v

upstream raw materials:

2,6-Diacetylpyridine

ortho-ethylaniline

Downstream raw materials:

2,6-bis[1-(2-ethylphenylimino)ethyl]pyridinecobalt(II) chloride-tetrahydrofuran (1/1)

[FeCl₂(2,6-bis[1-(2-ethylphenylimino)ethyl]-pyridine)]

RhCl[2,6-bis{1-(2-ethylphenyl)iminoethyl}pyridine]

[FeCl₃(2,6-bis[1-(2-ethylphenylimino)ethyl]pyridine)]