2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine

Base Information

• Chemical Name: 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine
• CAS No.: 168984-99-4
• Molecular Formula: C₁₈H₂₀ClNO₂S
• Molecular Weight: 349.881
• Mol file: 168984-99-4.mol

Synonyms:2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine

Chemical Property of 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine

Chemical Property:

Purity/Quality:

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Technology Process of 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine

There total 8 articles about 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-(4-Chloro-phenyl)-1-(toluene-4-sulfonyl)-2-trimethylsilanylmethyl-pyrrolidine → 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine (168984-99-4)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1016/0040-4039(96)01975-2

Reference yield: 91.0%

N-(p-toluenesulfonyl)-2-(4-chlorophenyl)aziridine (97401-93-9) + allylmagnesium bromide (1730-25-2) → 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine (168984-99-4)

Guidance literature:

In tetrahydrofuran; diethyl ether; for 1h; Ambient temperature;

DOI:10.1080/00397919508015419

Reference yield: 85.0%

tetraallyl tin (7393-43-3) + N-(p-toluenesulfonyl)-2-(4-chlorophenyl)aziridine (97401-93-9) → 2-(p-chlorophenyl)-N-(p-toluenesulfonyl)-pent-4-en-1-amine (168984-99-4)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(03)01559-4

upstream raw materials:

N-(p-toluenesulfonyl)-2-(4-chlorophenyl)aziridine

allylmagnesium bromide

allyl-trimethyl-silane

tetraallyl tin