2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Base Information

Chemical Name:2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol
CAS No.:467252-65-9
Molecular Formula:C₁₄H₁₇N₃O₃S
Molecular Weight:307.373
Hs Code.:

Synonyms:2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Suppliers and Price of 2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

There total 5 articles about 2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 13182-81-5
1-(2-chloroethyl)-2-methyl-5-nitro-1H-imidazole

: 339354-89-1
2-methyl-3-sulfanylbenzyl alcohol

: 467252-65-9
2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Guidance literature:: With potassium carbonate; for 5h; Heating;
DOI:10.1021/jm0208673

Reference yield:

: 1975-50-4
2-methyl-3-nitrobenzic acid

: 467252-65-9
2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Guidance literature:: Multi-step reaction with 5 steps

1.1: H₂ / Pd/C

2.1: NaNO₂; H⁺

2.2: potassium ethyl xanthogenate; aq. Na₂CO₃ / pH 8

2.3: 14.66 g / aq. NaOH / 20 h / Heating

3.1: 93 percent / H₂SO₄ / 48 h / Heating

4.1: 96 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

5.1: 56 percent / K₂CO₃ / 5 h / Heating

With lithium aluminium tetrahydride; sulfuric acid; hydrogen; hydrogen cation; potassium carbonate; sodium nitrite; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1021/jm0208673

Reference yield:

: 52130-17-3
3-amino-2-methylbenzoic acid

: 467252-65-9
2-methyl-3-[2-(2-methyl-5-nitroimidazol-1-yl)ethylsulfanyl]benzyl alcohol

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaNO₂; H⁺

1.2: potassium ethyl xanthogenate; aq. Na₂CO₃ / pH 8

1.3: 14.66 g / aq. NaOH / 20 h / Heating

2.1: 93 percent / H₂SO₄ / 48 h / Heating

3.1: 96 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

4.1: 56 percent / K₂CO₃ / 5 h / Heating

With lithium aluminium tetrahydride; sulfuric acid; hydrogen cation; potassium carbonate; sodium nitrite; In tetrahydrofuran;
DOI:10.1021/jm0208673