3-Ethoxycarbonylquinolizidine

Base Information

• Chemical Name: 3-Ethoxycarbonylquinolizidine
• CAS No.: 19728-76-8
• Molecular Formula: C₁₂H₂₁NO₂
• Molecular Weight: 211.304
• Mol file: 19728-76-8.mol

Synonyms:Octahydroquinolizine-3-carboxylic acid ethyl ester;3-ethoxycarbonylquinolizidine;cis-octahydro-2h-quinolizine-3-carboxylic acid ethyl ester

Chemical Property of 3-Ethoxycarbonylquinolizidine

Chemical Property:

• Vapor Pressure: 0.0036mmHg at 25°C
• Refractive Index: 1.502
• Boiling Point: 95-96 ºC (2 Torr)
• PKA: 9.42±0.40(Predicted)
• Flash Point: 99 ºC
• PSA: 29.54000
• Density: 1.05 g/cm³
• LogP: 1.75190
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

cis-Ethyloctahydro-1H-quinolizine-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Ethoxycarbonylquinolizidine

There total 16 articles about 3-Ethoxycarbonylquinolizidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-aminomethyl-octahydro-quinolizin-4-one + (+/-)-(9ar)-octahydro-quinolizin-3c-carboxylic acid ethyl ester (19728-76-8,19728-77-9,76211-05-7)

Guidance literature:

With hydrogenchloride; platinum; Hydrogenation_.Nebenpr_. 2: (+-)-(9ar)-Octahydro-chinolizin-3t-carbonsaeure-aethylester;

DOI:10.1021/ja01109a059

Reference yield:

→ (+/-)-(9ar)-octahydro-quinolizin-3c-carboxylic acid ethyl ester (19728-76-8,19728-77-9,76211-05-7) + (+/-)-(9ar)-octahydro-quinolizin-3t-carboxylic acid ethyl ester (19728-76-8,19728-77-9,76211-05-7)

Guidance literature:

With hydrogenchloride; platinum; Hydrogenation;

DOI:10.1021/ja01109a059

Reference yield:

→ (+/-)-(9ar)-octahydro-quinolizin-3c-carboxylic acid ethyl ester (19728-76-8,19728-77-9,76211-05-7) + (+/-)-(9ar)-octahydro-quinolizin-3t-carboxylic acid ethyl ester (19728-76-8,19728-77-9,76211-05-7)

Guidance literature:

With hydrogenchloride; platinum; Hydrogenation;

DOI:10.1021/ja01109a059

upstream raw materials:

(2-[2]piperidyl-ethyl)-malonic acid diethyl ester

sodium ethanolate

(+/-)-(9ar)-octahydro-quinolizin-3t-carboxylic acid ethyl ester

ethanol

Downstream raw materials:

(+/-)-(9ar)-octahydro-quinolizin-3c-carboxylic acid ethyl ester

(+/-)-3t-(toluene-4-sulfonyloximethyl)-(9ar)-octahydro-quinolizin

(+/-)-octahydro-3,5-methano-quinolizinium; picrate

(+/-)-N-[(9ar)-octahydroquinolizin-3t-yl-N'-phenyl-urea

Refernces