N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide)

Base Information

• Chemical Name: N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide)
• CAS No.: 256429-28-4
• Molecular Formula: C₂₆H₁₈F₂N₂O₂S₂
• Molecular Weight: 492.57
• Mol file: 256429-28-4.mol

Synonyms:N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide)

Chemical Property of N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide)

There total 1 articles about N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-fluorobenzoyl chloride (403-43-0) + 2-Aminophenyl disulfide (1141-88-4) → N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide) (256429-28-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1246/bcsj.70.1077

Reference yield: 92.0%

(Et4N)2(Fe4S4(SPh)4) + N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide) (256429-28-4) → [(C2H5)4N]2[Fe4S4(2-(4-fluorobenzoylamino)benzenethiolate)4]

Guidance literature:

In acetonitrile; Ar atmosphere, stirring (room temperature, overnight); concn. (reduced pressure), washing (Et2O), recrystn. (CH3CN/Et2O), drying (vacuum); elem. anal.;

DOI:10.1246/bcsj.70.1077

Reference yield: 46.0%

triiron dodecarbonyl (17685-52-8) + N,N’-(disulfanediylbis(2,1-phenylene))bis(4-fluorobenzamide) (256429-28-4) → [(μ-S-2-(4-FC6H4CONHC6H4))2Fe2(CO)6] (1035114-09-0)

Guidance literature:

In tetrahydrofuran; under N2; Fe3(CO)12 (5.95 mmol) was suspended in THF followed by addn. of a ligand (5.95 mmol); stirring at 70°C for ca. 10 h; the mixt. was cooled to room temp. and filtered; the red filtrate was evapd. to dryness under vac.; chromy. (silica gel, n-hexane/CH2Cl2); elem.anal.;

DOI:10.1039/b715990k

upstream raw materials:

4-fluorobenzoyl chloride

2-Aminophenyl disulfide

Downstream raw materials:

[(μ-S-2-(4-FC6H4CONHC6H4))2Fe2(CO)6]