2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Base Information

Chemical Name:2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate
CAS No.:1242157-24-9
Molecular Formula:C₂₁H₂₀ClFN₂O₃
Molecular Weight:402.853
Hs Code.:

Synonyms:2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Suppliers and Price of 2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

There total 4 articles about 2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1242156-61-1
6-tert-butyl-2-(3-chloro-2-(hydroxymethyl)phenyl)-8-fluorophthalazin-1(2H)-one

: 108-24-7
acetic anhydride

: 1242157-24-9
2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Guidance literature:: With dmap; In dichloromethane; at 4 ℃; for 3h;

Reference yield:

: 387-45-1
2-chloro-6-fluorobenzaldehyde

: 1242157-24-9
2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate; ethyl trimethylsilyl ether / N,N-dimethyl-formamide / 5 h / 62 °C / Inert atmosphere

2: sodium tetrahydroborate; isopropyl alcohol / dichloromethane / 3 h / 4 °C

3: dmap / dichloromethane / 3 h / 4 °C

With dmap; sodium tetrahydroborate; ethyl trimethylsilyl ether; caesium carbonate; isopropyl alcohol; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1242156-59-7
6-(tert-butyl)-8-fluorophthalazin-1(2H)-one

: 1242157-24-9
2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate; ethyl trimethylsilyl ether / N,N-dimethyl-formamide / 5 h / 62 °C / Inert atmosphere

2: sodium tetrahydroborate; isopropyl alcohol / dichloromethane / 3 h / 4 °C

3: dmap / dichloromethane / 3 h / 4 °C

With dmap; sodium tetrahydroborate; ethyl trimethylsilyl ether; caesium carbonate; isopropyl alcohol; In dichloromethane; N,N-dimethyl-formamide;