Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester

Base Information

Chemical Name:Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester
CAS No.:212513-20-7
Molecular Formula:C₃₂H₃₄O₇
Molecular Weight:530.618
Hs Code.:

Synonyms:Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester

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Chemical Property of Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester

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Technology Process of Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester

There total 2 articles about Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 212513-10-5
methyl (R)-2-[((tert-butylthio)carbonyl)acetyloxy]-3-triphenylmethyloxypropionate

: 108-93-0
cyclohexanol

: 212513-20-7
Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester

Guidance literature:: With silver trifluoroacetate; In tetrahydrofuran; at 23 ℃;
DOI:10.1021/jm0100741

Reference yield:

: 16814-88-3
methyl (2R)-2-methoxy-3-(triphenylmethoxy)propanoate

: 212513-20-7
Malonic acid cyclohexyl ester (R)-1-methoxycarbonyl-2-trityloxy-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / DCC / CH₂Cl₂ / 2 h / 0 °C

2: silver trifluoroacetate / tetrahydrofuran / 23 °C

With silver trifluoroacetate; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm0100741