Technology Process of 5-(2-chlorophenyl)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,4-triazole
There total 3 articles about 5-(2-chlorophenyl)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,4-triazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C14H17N3O2*2ClH; 2-chlorobenzoylhydrazide;
With
ammonium acetate; acetic acid;
at 150 ℃;
for 1h;
With
sodium hydrogencarbonate;
In
water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / dimethyl sulfoxide / 1 h / 120 °C
2: hydrogenchloride / diethyl ether / 0 - 20 °C
3: ammonium acetate; acetic acid / 1 h / 150 °C
With
hydrogenchloride; ammonium acetate; potassium carbonate; acetic acid;
In
diethyl ether; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogenchloride / diethyl ether / 0 - 20 °C
2: ammonium acetate; acetic acid / 1 h / 150 °C
With
hydrogenchloride; ammonium acetate; acetic acid;
In
diethyl ether;
