Technology Process of C28H24FN3O5*ClH
There total 9 articles about C28H24FN3O5*ClH which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: boron tribromide / dichloromethane / 19.5 h / 0 - 20 °C
2: 1H-imidazole / N,N-dimethyl-formamide / 0 - 20 °C
3: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 1 h / 20 °C
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
5: caesium carbonate; N,N-dimethylaminoglycine; copper(l) iodide / 1,4-dioxane / 24 h / Inert atmosphere; Reflux
With
1H-imidazole; copper(l) iodide; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; boron tribromide; N,N-dimethylaminoglycine; caesium carbonate; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
With
copper(l) iodide; N,N-dimethylaminoglycine; caesium carbonate;
In
1,4-dioxane;
for 24h;
Inert atmosphere;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogenchloride / isopropyl alcohol; 1,4-dioxane / 1 h / 120 °C / Sealed tube
2: caesium carbonate; N,N-dimethylaminoglycine; copper(l) iodide / 1,4-dioxane / 24 h / Inert atmosphere; Reflux
With
hydrogenchloride; copper(l) iodide; N,N-dimethylaminoglycine; caesium carbonate;
In
1,4-dioxane; isopropyl alcohol;