Technology Process of 3,5-diiodo-N-[2,6-bis(3,5-diisopropylphenyl)phenyl]salicylaldimine
There total 5 articles about 3,5-diiodo-N-[2,6-bis(3,5-diisopropylphenyl)phenyl]salicylaldimine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
methanol;
at 20 - 65 ℃;
for 15.5h;
DOI:10.1021/ja411945n
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium nitrite; hydrogenchloride / water / 0.17 h / -5 °C
1.2: 48 h / 4 - 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C
2.2: trialkyl borate / 2 h / -78 - 20 °C
2.3: pH 2
3.1: bis(dibenzylideneacetone)-palladium(0); triphenylphosphine / toluene / 0.17 h / 20 °C
3.2: 21 h / 20 °C / Heating
3.3: air / 1 h
4.1: toluene-4-sulfonic acid / methanol / 15.5 h / 20 - 65 °C
With
hydrogenchloride; n-butyllithium; toluene-4-sulfonic acid; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0); sodium nitrite;
In
tetrahydrofuran; methanol; hexane; water; toluene;
3.1: |Suzuki Coupling;
DOI:10.1021/ja411945n
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: bis(dibenzylideneacetone)-palladium(0); triphenylphosphine / toluene / 0.17 h / 20 °C
1.2: 21 h / 20 °C / Heating
1.3: air / 1 h
2.1: toluene-4-sulfonic acid / methanol / 15.5 h / 20 - 65 °C
With
toluene-4-sulfonic acid; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0);
In
methanol; toluene;
1.1: |Suzuki Coupling;
DOI:10.1021/ja411945n
