2631-77-8

Basic information

• Product Name: 3,5-DIIODOSALICYLALDEHYDE
• Synonyms: 3,5-DIIODOSALICYLALDEHYDE;3,5-DIIODO-2-HYDROXYBENZALDEHYDE;AKOS BBS-00003265;2-HYDROXY-3,5-DIIODOBENZALDEHYDE;Benzaldehyde, 2-hydroxy-3,5-diiodo-;3,5-Diiodo-2-hydroxybenzaldehyde~2-Hydroxy-3,5-diiodobenzaldehyde;3,5-Diodosolicylaldehyde;3,5-Diiodo-4-Hydroxybenzaldhyd
• CAS NO: 2631-77-8
• Molecular Formula: C7H4I2O2
• Molecular Weight: 373.91
• EINECS: 220-117-2
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Aldehydes;C7;Carbonyl Compounds
• Mol File: 2631-77-8.mol
• Article Data: 69

Chemical Properties

• Melting Point: 109-110 °C(lit.)
• Boiling Point: 304.6 °C at 760 mmHg
• Flash Point: 138 °C
• Appearance: pale yellow powder
• Density: 2.602 g/cm³
• Vapor Pressure: 0.000481mmHg at 25°C
• Refractive Index: 1.787
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 6.12±0.23(Predicted)
• Water Solubility: Insoluble in water.
• Sensitive: Air & Light Sensitive
• BRN: 1102552
• CAS DataBase Reference: 3,5-DIIODOSALICYLALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIIODOSALICYLALDEHYDE(2631-77-8)
• EPA Substance Registry System: 3,5-DIIODOSALICYLALDEHYDE(2631-77-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 2631-77-8(Hazardous Substances Data)

Usage

Uses

3,5-Diiodosalicylaldehyde is used to synthesize new Schiff bases, (2,4-diiodo-6-[(2-morpholin-4-yl-ethylimino)-methyl]-phenol and 2,4-diiodo-6-[(3-morpholin-4-yl-propylimino)-methyl]-phenol) and the new tridentate ligand, [(2-hydroxy-3,5-diiodo-benzylidene)-amino]-acetic acid (HDBA), 3-bromo-N?-(2-hydroxy-3,5-diiodobenzylidene)benzohydrazide monohydrate.

InChI:InChI=1/C7H4I2O2/c8-5-1-4(3-10)7(11)6(9)2-5/h1-3,11H

Upstream product

• 24123-68-0 2,2-dibromo-1-(2,4-dichlorophenyl)ethanone 
• 121-45-9 phosphorous acid trimethyl ester 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 13094-51-4 bromoacetic anhydride 
• 541-73-1 1,3-Dichlorobenzene 
• 598-21-0 2-Bromoacetyl bromide 
• 89-95-2 2-methyl-benzyl alcohol 
• 90-02-8 salicylaldehyde 
• 60-29-7 diethyl ether 
• 7732-18-5 water 
• 22118-09-8 2-bromoacetyl chloride 

Downstream Products

• 133-91-5 3,5-diiodosalicylic acid 
• 21405-40-3 2-hydroxy-3,5-diiodo-benzaldehyde-oxime 
• 143159-49-3 2,4-diiodo-6-(phenylimino-methyl)-phenol 
• 88070-27-3 2-hydroxy-3,5-diiodo-benzaldehyde-thiosemicarbazone 
• 101422-40-6 3-benzoyl-6,8-diiodo-coumarin 
• 958635-03-5 N,N'-bis(3',5'-diiodosalicylidene)-(1S)-ortho-chlorophenyl-1,2-ethylenediamine 
• 958635-08-0 N,N'-bis(3',5'-diiodosalicylidene)-(1R)-(α-naphthylmethyl)-1,2-ethylenediamine 
• 1345846-36-7 C₂₀H₂₁BrI₂N₄O₂ 

Relevant articles and documents

Synthesis and crystal structure of 2,4-diiodo-6-[(2-morpholin-4-yl- ethylimino)-methyl]-phenolato-zinc(II)

One new complex, 2,4-Diiodo-6-[(2-morpholin-4-yl-ethylimino)- methyl]- phenolato-zinc(II) has been designed and synthesized. The structure was determined by UV, IR and single X-ray crystallography study. The title complex C26H30O4N4I4Zn crystallizes in the triclinic space group P - 1 with the cell parameters a = 9.938(2) A, b = 11.937(2) A, c = 14.527(3) A, α = 87.14(3)°, β = 79.03(3)°, γ = 76.20(3)°, V = 1565.1(5) A3 and Z = 2. The central zinc(II) is four coordinate and bonds to two nitrogen atoms and two oxygen atoms from two 3,5-diiodosalicylaldehyde- 2- morpholinoethylamine Schiff bases. The complex is linked into a column by weak intermolecular interactions.

BuChE-IDO1 inhibitor as well as preparation method and application thereof

The invention relates to the field of medicines, and particularly discloses a BuChE-IDO1 inhibitor as well as a preparation method and application thereof. The 7-chlorine-3-substituted benzothiophene part of sertaconazole is chemically modified, the influence of the 7-chlorine-3-substituted benzothiophene part of sertaconazole on the in-vitro inhibitory activity of AChE, BuChE and IDO1 is explored, the target compound is further optimized, and the technical problems that an existing BuChE-IDO1 inhibitor is poor in pertinence and safety are solved. What is explored is that an appropriate substituent group introduced to a 2-benzothiazole ring can form additional interaction with surrounding amino acids and heme iron, so that the binding affinity of the analogue with BuChE and IDO1 is increased, and a new idea is broadened for more efficient and targeted treatment of advanced AD diseases.

Antifungal water-soluble compound as well as preparation method and application thereof (by machine translation)

The invention provides an antifungal water-soluble compound, a preparation method thereof and application, of the compound as I shown in formula. The compound has good antifungal effect and water solubility, can be used for treating and preventing,configuration optical isomers of the optical isomer SRSS obtained by chiral synthesis. (by machine translation)

Imidazole compound and preparation method and application thereof, organic solderable protective agent containing imidazole compound and surface treatment method

The invention relates to the technical field of precious metal surface treatment, and in particular, relates to the technical field of copper or copper alloy surface protection materials. The invention discloses a dichlorophenyl imidazole compound, an application of the dichlorophenyl imidazole compound serving as a film forming matter of an organic solderable protective agent, and an organic solderable protective agent. The invention also discloses an application of the compound in copper or copper alloy surface anti-oxidation treatment, and a surface treatment method of the copper or copperalloy, wherein the method comprises the following steps: infiltrating the surface of the copper or copper alloy with the organic weldable protective agent containing the compound, and drying to generate a coating layer on the surface.