Technology Process of C28H25N3O
There total 5 articles about C28H25N3O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; XPhos;
In
toluene;
at 80 ℃;
for 24h;
Inert atmosphere;
DOI:10.1016/j.dyepig.2012.09.001
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / 85 °C
2.1: N-iodo-succinimide / tetrahydrofuran / 4 h / 20 °C
3.1: n-butyllithium / tetrahydrofuran / 1 h / 0 - 20 °C
3.2: 3 h / -78 - 20 °C
4.1: XPhos; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate / toluene / 24 h / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); N-iodo-succinimide; n-butyllithium; caesium carbonate; toluene-4-sulfonic acid; sodium t-butanolate; XPhos;
In
tetrahydrofuran; toluene;
1.1: |Fischer Indole Synthesis;
DOI:10.1039/c2jm33228k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-iodo-succinimide / tetrahydrofuran / 4 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran / 1 h / 0 - 20 °C
2.2: 3 h / -78 - 20 °C
3.1: XPhos; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate / toluene / 24 h / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); N-iodo-succinimide; n-butyllithium; caesium carbonate; sodium t-butanolate; XPhos;
In
tetrahydrofuran; toluene;
DOI:10.1039/c2jm33228k
