Quinoline-6-boronic acid

Base Information

Chemical Name:Quinoline-6-boronic acid
CAS No.:376581-24-7
Molecular Formula:C₉H₈BNO₂
Molecular Weight:172.979
Hs Code.:29334990
European Community (EC) Number:691-953-7
DSSTox Substance ID:DTXSID40400626
Nikkaji Number:J2.725.429B
Wikidata:Q72505813
Mol file:376581-24-7.mol

Synonyms:Boronicacid, 6-quinolinyl- (9CI);Quinolin-6-ylboronic acid;Quinoline-6-boronic acid;

Suppliers and Price of Quinoline-6-boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Quinoline-6-boronic acid
1g
$ 358.00

TRC
Quinoline-6-boronicAcid
50mg
$ 60.00

Matrix Scientific
Quinolin-6-ylboronic acid
1g
$ 50.00

Matrix Scientific
Quinolin-6-ylboronic acid
5g
$ 180.00

Labseeker
Quinoline-6-BoronicAcid 95
25g
$ 462.00

JR MediChem
Quinoline-6-boronicacid 98%
5g
$ 145.00

J&W Pharmlab
Quinoline-6-boronicacid 97%
1g
$ 50.00

J&W Pharmlab
Quinoline-6-boronicacid 97%
25g
$ 720.00

J&W Pharmlab
Quinoline-6-boronicacid 97%
5g
$ 160.00

ChemScene
Boronicacid,B-6-quinolinyl- 98.94%
25g
$ 343.00

Total 71 raw suppliers

Chemical Property of Quinoline-6-boronic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:106-109°C
Refractive Index:1.645
Boiling Point:400.261 °C at 760 mmHg
PKA:7.70±0.30(Predicted)
Flash Point:195.871 °C
PSA：53.35000
Density:1.289 g/cm³
LogP:-0.08540
Storage Temp.:Keep Cold
Water Solubility.:Slightly soluble in water.
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:173.0648087
Heavy Atom Count:13
Complexity:177

Purity/Quality:

99% ^*data from raw suppliers

Quinoline-6-boronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-36/38-22
Safety Statements: 26-36/37/39-37/39

MSDS Files:

Useful:

Canonical SMILES:B(C1=CC2=C(C=C1)N=CC=C2)(O)O
Uses It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of Quinoline-6-boronic acid

There total 4 articles about Quinoline-6-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.4%

: 406463-06-7
6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)quinoline

: 376581-24-7
6-quinolineboronic acid

Guidance literature:: With hydrogenchloride; at 50 ℃; for 0.5h;

Reference yield:

: 6-bromoquinoline hydrochloride

: 7732-18-5
water

: 73183-34-3
bis(pinacol)diborane

: 376581-24-7
6-quinolineboronic acid

Guidance literature:: 6-bromoquinoline hydrochloride; bis(pinacol)diborane; With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 80 ℃; for 3h; Inert atmosphere; Sealed tube;

water; In ethyl acetate;

Reference yield:

: 5332-25-2
6-bromoquinoline

: 121-43-7,63156-11-6
Trimethyl borate

: 376581-24-7
6-quinolineboronic acid

Guidance literature:: 6-bromoquinoline; With n-butyllithium; In tetrahydrofuran; hexane; at -30 ℃; Inert atmosphere; Flow reactor;

Trimethyl borate; In tetrahydrofuran; hexane; at -30 ℃; Inert atmosphere; Flow reactor;
DOI:10.1021/acs.orglett.6b01681