Stearyl glycyrrhetinate

Base Information

Chemical Name:Stearyl glycyrrhetinate
CAS No.:13832-70-7
Molecular Formula:C48H82 O4
Molecular Weight:723.16
Hs Code.:2918990090
European Community (EC) Number:604-071-4
UNII:3YYE6VJS0P
DSSTox Substance ID:DTXSID801313777
Nikkaji Number:J185.685E
Wikidata:Q27258219
RXCUI:1356147
Mol file:13832-70-7.mol

Synonyms:stearyl glycyrrhetinate

Suppliers and Price of Stearyl glycyrrhetinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Stearyl Glycyrrhetinate
500mg
$ 60.00

TCI Chemical
Stearyl Glycyrrhetinate >98.0%(HPLC)
5g
$ 45.00

TCI Chemical
Stearyl Glycyrrhetinate >98.0%(HPLC)
25g
$ 156.00

Sigma-Aldrich
Stearyl glycyrrhetinate ≥95.0%
10g
$ 80.70

ChemScene
Stearyl Glycyrrhetinate ≥97.0%
5g
$ 78.00

Chem-Impex
Stearylglycyrrhetinate,≥98%(HPLC) ≥98%(HPLC)
5G
$ 48.92

Chem-Impex
Stearylglycyrrhetinate,98%(HPLC) 98%(HPLC)
25G
$ 178.08

American Custom Chemicals Corporation
STEARYL GLYCYRRHETINATE 95.00%
10G
$ 262.50

AK Scientific
Stearyl Glycyrrhetinate
5g
$ 40.00

Total 109 raw suppliers

Chemical Property of Stearyl glycyrrhetinate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:70-77 °C
Boiling Point:732.5°Cat760mmHg
PKA:15.11±0.70(Predicted)
Flash Point:198.8°C
PSA：63.60000
Density:1.01g/cm³
LogP:13.13270
Water Solubility.:9μg/L at 20℃
XLogP3:15.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:19
Exact Mass:722.62131109
Heavy Atom Count:52
Complexity:1250

Purity/Quality:

99% ^*data from raw suppliers

Stearyl Glycyrrhetinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCCCCOC(=O)C1(CCC2(CCC3(C(=CC(=O)C4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C
Isomeric SMILES:CCCCCCCCCCCCCCCCCCOC(=O)[C@]1(CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2C1)C)C)C
Uses stearyl glycyrrhetinate is anti-inflammatory and soothing. This is the ester of stearyl alcohol and glycyrrhetinic acid, where stearyl alcohol helps improve the penetration of the functional component, glycyrrhetinic acid. Stearyl glycyrrhetinate can be used to prepare modified liposomes loaded with norcantharidin and 10-hydroxycamptothecin, which are used as drug delivery systems in cancer therapy.

Technology Process of Stearyl glycyrrhetinate

There total 4 articles about Stearyl glycyrrhetinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.4%

: 112-92-5
1-octadecanol

: 471-53-4
enoxolone

: 13832-70-7
glycyrrhetinyl stearate

Guidance literature:: With pyridine; 2-chloro-1,3-dimethyl imidazolium chloride; for 24h; Ambient temperature;
DOI:10.1016/0223-5234(96)89163-X

Reference yield:

: 471-53-4
enoxolone

: 112-89-0
1-Bromooctadecane

: 13832-70-7
glycyrrhetinyl stearate

Guidance literature:: enoxolone; With sodium hydroxide; In ethanol; water; at 50 ℃; for 0.5h; Ionic liquid;

1-Bromooctadecane; for 4h; Temperature; Reflux;