3-fluoroamphetamine

Base Information

• Chemical Name: 3-fluoroamphetamine
• CAS No.: 1335366-28-3
• Molecular Formula: C₉H₁₂FN
• Molecular Weight: 153.199
• Mol file: 1335366-28-3.mol

Synonyms:3-fluoroamphetamine

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Chemical Property of 3-fluoroamphetamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-fluoroamphetamine

There total 2 articles about 3-fluoroamphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(±)-1-(3-fluorophenyl)propan-2-amine (1626-71-7) → (S)‐1‐(4‐methoxyphenyl)propan‐2‐amine (1194056-02-4) + 3-fluoroamphetamine (1335366-28-3)

Guidance literature:

With column LiChrospher 100 RP-18e; sulfated β-cyclodextrin; In methanol; water; at 20 ℃; Reagent/catalyst;

DOI:10.1002/chir.22341

Reference yield:

(3-fluorophenyl)acetone (1737-19-5) → 3-fluoroamphetamine (1335366-28-3)

Guidance literature:

With ammonium hydroxide; ammonium acetate; GkAmDH; In water; at 40 ℃; for 24h; pH=9; Enzymatic reaction;

DOI:10.1039/d0cy00071j

upstream raw materials:

(±)-1-(3-fluorophenyl)propan-2-amine

(3-fluorophenyl)acetone

Refernces

• 1、 H?gele, Johannes S.,Schmid, Martin G.. "Enantiomeric separation of Novel Psychoactive Substances by capillary electrophoresis using (+)-18-crown-6-tetracarboxylic acid as chiral selector". . p. 1019 - 1026. Retrieved 2018/07/29.
• 2、 Taschwer, Magdalena,Seidl, Yvonne,Mohr, Stefan,Schmid, Martin G.. "Chiral separation of cathinone and amphetamine derivatives by HPLC/UV using sulfated β-cyclodextrin as chiral mobile phase additive". . p. 411 - 418. Retrieved 2014/08/05.