2-methyl-2-propenyl tosylate

Base Information

• Chemical Name: 2-methyl-2-propenyl tosylate
• CAS No.: 20443-62-3
• Molecular Formula: C₁₁H₁₄O₃S
• Molecular Weight: 226.296
• Mol file: 20443-62-3.mol

Synonyms:2-methyl-2-propenyl tosylate

Chemical Property of 2-methyl-2-propenyl tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-2-propenyl tosylate

There total 2 articles about 2-methyl-2-propenyl tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

p-toluenesulfonyl chloride (98-59-9) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 2-methyl-2-propenyl tosylate (20443-62-3)

Guidance literature:

With trimethylamine hydrochloride; triethylamine; In toluene; at 0 - 5 ℃; for 1h;

DOI:10.1016/S0040-4020(99)00002-2

Reference yield:

→ 2-methyl-2-propenyl tosylate (20443-62-3)

Guidance literature:

Toluol-4-sulfochlorid, 2-Methyl-prop-2-en-1-ol, Kaliumhydroxid in Ae.;

Reference yield: 71.0%

CpFe(CO)2(C6H4(Bpin)-4) (1048699-48-4) + 2-methyl-2-propenyl tosylate (20443-62-3) → CH2C(CH3)CH2C6H4BO2C2(CH3)4 (1048699-47-3)

Guidance literature:

In tetrahydrofuran; Irradiation (UV/VIS); for 1 h at 25°C;

DOI:10.1021/om800560m

upstream raw materials:

p-toluenesulfonyl chloride

3-hydroxy-2-methyl-1-propene

Downstream raw materials:

N-methallyl-p-toluidine

N,N-bis-(2-methylprop-2-enyl)-p-toluidine

(2,4-Dimethyl-phenyl)-bis-(2-methyl-allyl)-amine

Bis-(2-methyl-allyl)-(3-nitro-phenyl)-amine

Refernces

• 1、 Gustin, Darin J.,Li, Yihong,Brown, Matthew L.,Min, Xiaoshan,Schmitt, Mike J.,Wanska, Malgorzata,Wang, Xiaodong,Connors, Richard,Johnstone, Sheere,Cardozo, Mario,Cheng, Alan C.,Jeffries, Shawn,Franks, Brendon,Li, Shyun,Shen, Shanling,Wong, Mariwil,Wesche, Holger,Xu, Guifen,Carlson, Timothy J.,Plant, Matthew,Morgenstern, Kurt,Rex, Karen,Schmitt, Joanna,Coxon, Angela,Walker, Nigel,Kayser, Frank,Wang, Zhulun. "Structure guided design of a series of sphingosine kinase (SphK) inhibitors". . p. 4608 - 4616. Retrieved 2013/08/15.
• 2、 Hoffmann,Brueckner. "Stereoselective synthesis of alcohols. Part LV. Domino hydroformylation-allylboration-hydroformylation reactions to give trans-perhydropyrano[3,2-b] pyridine derivatives". . p. 369 - 373. Retrieved 2007/10/03.