(R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid

Base Information

• Chemical Name: (R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid
• CAS No.: 348081-10-7
• Molecular Formula: C₁₇H₁₅NO₄S₂
• Molecular Weight: 361.442
• Mol file: 348081-10-7.mol

Synonyms:(R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid

Chemical Property of (R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid

There total 1 articles about (R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-phenylglycine (875-74-1) + benzo[b]thiophene-5-methanesulfonyl chloride (348080-83-1) → (R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid (348081-10-7)

Guidance literature:

With pyridine; N,O-Bis(trimethylsilyl)trifluoroacetamide; In N,N-dimethyl-formamide; at 0 - 55 ℃; for 2.5h;

Reference yield:

(R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-2-phenylacetic acid (348081-10-7) + O-(tert-butyldimethylsilanyl)hydroxylamine (41879-39-4) → (R)-2-(benzo[b]thiophen-5-ylmethanesulfonylamino)-N-(t-butyldimethylsilyloxy)-2-phenylacetamide

Guidance literature:

With 3-{[(ethylimino)methylene]-amino}-N,N,N-trimethyl-1-propanaminium iodide; In dichloromethane; at 0 - 20 ℃; for 2h;

upstream raw materials:

(R)-phenylglycine

benzo[b]thiophene-5-methanesulfonyl chloride