N-[(Trimethylsilyl)methyl]benzylamine

Base Information

• Chemical Name: N-[(Trimethylsilyl)methyl]benzylamine
• CAS No.: 53215-95-5
• Molecular Formula: C11H19NSi
• Molecular Weight: 193.364
• Hs Code.: 29319090
• Mol file: 53215-95-5.mol

Synonyms:N-Benzyl-N-[(trimethylsilyl)methyl]amine;N-Benzyltrimethylsilylmethylamine;

Chemical Property of N-[(Trimethylsilyl)methyl]benzylamine

Chemical Property:

• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: n20/D 1.496(lit.)
• Boiling Point: 231.9 °C at 760 mmHg
• PKA: 9.29±0.20(Predicted)
• Flash Point: 96.1 °C
• PSA: 12.03000
• Density: 0.893 g/cm³
• LogP: 3.46280
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

N-Benzyl-1-(trimethylsilyl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-[(Trimethylsilyl)methyl]benzylamine may be used in chemical synthesis.

Technology Process of N-[(Trimethylsilyl)methyl]benzylamine

There total 5 articles about N-[(Trimethylsilyl)methyl]benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzylamine (100-46-9) + Chloromethyltrimethylsilane (2344-80-1) → N-(trimethylsilylmethyl)benzylamine (53215-95-5)

Guidance literature:

In dimethyl sulfoxide; Heating;

DOI:10.1016/0040-4020(96)00190-1

Reference yield: 89.0%

iodo(trimethylsilyl)methane (4206-67-1) + benzylamine (100-46-9) → N-(trimethylsilylmethyl)benzylamine (53215-95-5)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2014.10.060

Reference yield:

C4H12ClNSi + benzylamine (100-46-9) → N-(trimethylsilylmethyl)benzylamine (53215-95-5)

Guidance literature:

In acetonitrile; for 16h; Inert atmosphere; Reflux;

DOI:10.1021/acs.joc.5b02845

upstream raw materials:

benzylamine

Chloromethyltrimethylsilane

(trimethylsilyl)methyl 4-methylbenzenesulfonate

iodo(trimethylsilyl)methane

Downstream raw materials:

N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine

C₁₃H₂₁⁽²⁾H₂NOSi

N-benzyl-N-(cyanomethyl)-N-[(trimethylsilyl)methyl]amine

N,N'-dibenzyl-N,N'-bis-<(trimethylsilyl)methyl>diaminomethane