Tulathromycin A

Base Information

Chemical Name:Tulathromycin A
CAS No.:217500-96-4
Molecular Formula:C₄₁H₇₉N₃O₁₂
Molecular Weight:806.091
Hs Code.:
European Community (EC) Number:638-829-0
UNII:897A3KN7AP
DSSTox Substance ID:DTXSID60274184
Nikkaji Number:J1.801.351G
Wikipedia:Tulathromycin
Wikidata:Q7851973
NCI Thesaurus Code:C81443
RXCUI:1437806
Metabolomics Workbench ID:144454
Mol file:217500-96-4.mol

Synonyms:draxxin;tulathromycin

Suppliers and Price of Tulathromycin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tulathromycin A
100mg
$ 389.00

TRC
TulathromycinA
10mg
$ 145.00

DC Chemicals
TulathromycinA 99%
1 g
$ 1200.00

DC Chemicals
TulathromycinA 99%
100 mg
$ 300.00

DC Chemicals
TulathromycinA 99%
250 mg
$ 600.00

Crysdot
TulathromycinA 98+%
100mg
$ 636.00

Crysdot
TulathromycinA 98+%
50mg
$ 502.00

ChemScene
TulathromycinA >98.0%
25mg
$ 155.00

ChemScene
TulathromycinA >98.0%
100mg
$ 437.00

ChemScene
TulathromycinA >98.0%
50mg
$ 285.00

Total 159 raw suppliers

Chemical Property of Tulathromycin A

Chemical Property:

Boiling Point:853.8±65.0 °C(Predicted)
PKA:13.19±0.70(Predicted)
PSA：200.90000
Density:1.17
LogP:2.64800
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:3.8
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:11
Exact Mass:805.56637496
Heavy Atom Count:56
Complexity:1240

Purity/Quality:

99% ^*data from raw suppliers

Tulathromycin A ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCNCC1(C(OC(CC1(C)OC)OC2C(C(C(CC(CNC(C(C(C(OC(=O)C2C)CC)(C)O)O)C)C)(C)O)OC3C(C(CC(O3)C)N(C)C)O)C)C)O
Isomeric SMILES:CCCNC[C@@]1([C@@H](O[C@H](C[C@@]1(C)OC)O[C@H]2[C@@H]([C@H]([C@](C[C@H](CN[C@@H]([C@H]([C@]([C@H](OC(=O)[C@@H]2C)CC)(C)O)O)C)C)(C)O)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)C)C)O
Uses Tulathromycin A is used for the treatment of pulmonary diseases in pigs and cattle. In cattle, tulathromycin is used for the treatment of rinderpest caused by Haemolytic rinderpest, polyvalent rinderpest and Haemophilus somnus (formerly Haemophilus somnus). It is also effective in the treatment of infections caused by Mycoplasma bovis. When used in high-risk calves, it is also used to prevent infections caused by these pathogens. It is also used for the treatment of bovine foot rot (interdigital necrotizing fungal disease) associated with Fusarium necrophorum and Fusarium oxysporum. A single dose is effective in bovine infectious keratoconjunctivitis (Mycobacterium bovis).In pigs, it is used to control and treat SRD associated with Actinobacillus pleuropneumoniae, Bacteroides multilocularis, Bordetella bronchiseptica, Mycoplasma pneumoniae, and Haemophilus parasiticus, and tulathromycin has been used to treat lung abscesses.
Description Tulathromycin A is a triamide antibiotic used for the treatment of respiratory diseases in cattle and pigs. It exists as a balanced mixture of two isomers. Tulathromycin is an antimicrobial agent of a macrolide, a 15-membered macrolide structure that is considered a triamide macrolide with three charged nitro groups.

Technology Process of Tulathromycin A

There total 69 articles about Tulathromycin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 107-10-8,42939-71-9
propylamine

: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]octan-6-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one

: 217500-96-4
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-Ο-methyl-4-C-[(propylamino)methyl]-α-L-ribohexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylohexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one

Guidance literature:: at 60 ℃;

Reference yield: 93.0%

: C₄₁H₇₇N₃O₁₂

: 217500-96-4
tulathromycin

Guidance literature:: With ammonia; hydrogen; In methanol; at 50 ℃; for 5h; under 3750.38 Torr; Reagent/catalyst; Temperature; Autoclave; Sealed tube;