4-N-BUTYLOXYBIPHENYL

Base Information

• Chemical Name: 4-N-BUTYLOXYBIPHENYL
• CAS No.: 108177-64-6
• Molecular Formula: C16H18O2
• Molecular Weight: 242.318
• Hs Code.: 2922299090
• Mol file: 108177-64-6.mol

Synonyms:4-(4-Butoxyphenyl)phenol;4-Butoxy-4'-hydroxybiphenyl;4-Hydroxy-4'-n-butoxybiphenyl;4'-Butyloxy-4-hydroxybiphenyl;

Chemical Property of 4-N-BUTYLOXYBIPHENYL

Chemical Property:

• Melting Point: 140-142 °C(Solv: ethanol (64-17-5))
• Boiling Point: 383.6 °C at 760 mmHg
• PKA: 10.01±0.26(Predicted)
• Flash Point: 197.3 °C
• PSA: 29.46000
• Density: 1.068±0.06 g/cm3(Predicted)
• LogP: 4.23810

Purity/Quality:

98%Min ^*data from raw suppliers

4-BUTOXY-4'-HYDROXYBIPHENYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-N-BUTYLOXYBIPHENYL

There total 2 articles about 4-N-BUTYLOXYBIPHENYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

1-bromo-butane (109-65-9) + 4,4'-Dihydroxybiphenyl (92-88-6) → 4-butoxy-4'-hydroxybiphenyl (108177-64-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 5h; Heating;

DOI:10.1055/s-2002-32534

Reference yield: 43.0%

1-iodo-butane (542-69-8) + 4,4'-Dihydroxybiphenyl (92-88-6) → 4-butoxy-4'-hydroxybiphenyl (108177-64-6)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 3h;

DOI:10.1081/SCC-120014771

Reference yield: 92.0%

4-butoxy-4'-hydroxybiphenyl (108177-64-6) + (3R,3aS,6R,6aR)-6-hydroxy-3-(4-methoxyphenyl)sulfonyloxyperhydrofuro[3,2-b]furan (72631-59-5) → C22H26O5

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 6h; Reflux;

DOI:10.1080/15421406.2013.833476

upstream raw materials:

1-bromo-butane

4,4'-Dihydroxybiphenyl

1-iodo-butane

Downstream raw materials:

[(4'-butyloxybiphenyl-4-yl)oxycarbonyl]phthalimide

N-[(S)-1-methylheptyl]-4-[(4'-butyloxybiphenyl-4-yl)oxycarbonyl]phthalimide

Refernces

• 1、 Chen, Hongru,Xue, Qingbin,Li, Zhuohua,Sun, Lingmin,Zhang, Quanxuan. "Synthesis and characterization of side chain polymer with helical PLLA segments containing mesogenic end group". . p. 400 - 408. Retrieved 2011.
• 2、 Xie, He-Lou,Ni, Bin,Liu, Quan,Wang, Jun,Yang, Shuang,Zhang, Hai-Liang,Chen, Er-Qiang. "Self organization of main-chain/side-chain liquid crystalline polymer based on "jacketing" effect with different lengths of spacer: From smectic to hierarchically ordered structure". . p. 97187 - 97194. Retrieved 2015.
• 3、 Cao, Ban-Peng,Shen, Chunyang,Xu, Yuan,Zhou, Qi,Morita, Yuki,Okamoto, Hiroaki,Xiao, Qiang. "Synthesis, liquid crystalline and gelation properties of 4-semifluoroalkoxybiphenyl derivatives". . . Retrieved 2019.