2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole

Base Information

• Chemical Name: 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole
• CAS No.: 250687-33-3
• Molecular Formula: C₁₇H₁₅NO₂S₇
• Molecular Weight: 489.774
• Mol file: 250687-33-3.mol

Synonyms:2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole

Chemical Property of 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole

There total 17 articles about 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4,5-bis(methylthio)-1,3-dithiole-2-thione (49638-64-4) + 5-tosyl-[1,3]dithiolo[4,5-c]pyrrol-2-one (250687-28-6) → 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole (250687-33-3)

Guidance literature:

With triethyl phosphite; at 130 ℃; Inert atmosphere;

DOI:10.3762/bjoc.11.96

Reference yield: 26.0%

4,5-bis(methylthio)-1,3-dithiol-2-one (61485-46-9) + 5-tosyl-5H-[1,3]dithiolo[4,5-c]pyrrole-2-thione (250687-27-5) → 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole (250687-33-3)

Guidance literature:

With triethyl phosphite; at 130 ℃; for 3.5h;

DOI:10.1021/ol9902428

Reference yield:

4,6-dihydro-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole-2-one (250687-26-4) → 2-[4,5-bis(methylthio)-1,3-dithiole-2-ylidene]-N-tosyl-(1,3)-dithiolo[4,5-c]pyrrole (250687-33-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / chlorobenzene / Heating

2: 57 percent / triethyl phosphite / 3.5 h / 130 °C

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; triethyl phosphite; In chlorobenzene;

DOI:10.1021/ol9902428

upstream raw materials:

4,5-bis(methylthio)-1,3-dithiole-2-thione

5-tosyl-[1,3]dithiolo[4,5-c]pyrrol-2-one

methyl iodide

4,5-bis(methylthio)-1,3-dithiol-2-one