4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE

Base Information

• Chemical Name: 4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE
• CAS No.: 61485-46-9
• Molecular Formula: C5H6OS4
• Molecular Weight: 210.36
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID60357542
• Nikkaji Number: J853.503E
• Wikidata: Q82137494
• Mol file: 61485-46-9.mol

Synonyms:4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE;4,5-BIS(METHYLTHIO)-1,3-DITHIOLE-2-ONE;RARECHEM AR PA 0058;4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE 97%

Chemical Property of 4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE

Chemical Property:

• Vapor Pressure: 0.000855mmHg at 25°C
• Melting Point: 56-60 °C(lit.)
• Refractive Index: 1.715
• Boiling Point: 304.8°C at 760 mmHg
• Flash Point: 134.5°C
• PSA: 124.15000
• Density: 1.5g/cm³
• LogP: 2.61360
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 209.93014950
• Heavy Atom Count: 10
• Complexity: 168

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,5-Bis(methylthio)-1,3-dithiol-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CSC1=C(SC(=O)S1)SC

Technology Process of 4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE

There total 5 articles about 4,5-BIS(METHYLTHIO)-1,3-DITHIOL-2-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4,5-bis(methylthio)-1,3-dithiole-2-thione (49638-64-4) → 4,5-bis(methylthio)-1,3-dithiol-2-one (61485-46-9)

Guidance literature:

With mercury(II) diacetate; In chloroform; acetic acid; for 5h; Heating;

Reference yield:

<1,2-Bis(methylthio)vinyl>-morpholinodithioformat (74962-32-6,74962-33-7) → 4,5-bis(methylthio)-1,3-dithiol-2-one (61485-46-9)

Guidance literature:

Multi-step reaction with 4 steps

1: Br₂ / CH₂Cl₂ / -30 °C

2: NaClO₄ / H₂O

3: 75 percent / H₂S / pyridine / 6 h / 0 °C

4: 85 percent / Hg(OAc)2 / CHCl₃; acetic acid / 5 h / Heating

With hydrogen sulfide; mercury(II) diacetate; sodium perchlorate; bromine; In pyridine; dichloromethane; chloroform; water; acetic acid;

Reference yield:

4,5-Bis(methylthio)-2-morpholino-1,3-dithiolium-bromid → 4,5-bis(methylthio)-1,3-dithiol-2-one (61485-46-9)

Guidance literature:

Multi-step reaction with 3 steps

1: NaClO₄ / H₂O

2: 75 percent / H₂S / pyridine / 6 h / 0 °C

3: 85 percent / Hg(OAc)2 / CHCl₃; acetic acid / 5 h / Heating

With hydrogen sulfide; mercury(II) diacetate; sodium perchlorate; In pyridine; chloroform; water; acetic acid;

upstream raw materials:

4,5-bis(methylthio)-1,3-dithiole-2-thione

2,5-diketo-1,3,4,6-tetrathiapentalene

methyl iodide

<1,2-Bis(methylthio)vinyl>-morpholinodithioformat

Downstream raw materials:

[2-(4,5-Bis-methylsulfanyl-[1,3]dithiol-2-ylidene)-6,7-dihydro-5H-[1,3]dithiolo[4,5-b][1,4]dithiepin-6-ylmethoxy]-tert-butyl-diphenyl-silane

tetrakis(methylthio)tetrathiafulvalene