Dexpanthenol iMpurity E

Base Information

• Chemical Name: Dexpanthenol iMpurity E
• CAS No.: 96305-22-5
• Molecular Formula: C₉H₁₄O₃
• Molecular Weight: 170.208
• Mol file: 96305-22-5.mol

Synonyms:dihydro-4,4-dimethyl-5-(1-methylethyl)-2,3-furandione

Chemical Property of Dexpanthenol iMpurity E

Chemical Property:

Purity/Quality:

>95% ^*data from raw suppliers

Dihydro-5-isopropyl-4,4-dimethyl-2,3-furandione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Dihydro-5-isopropyl-4,4-dimethyl-2,3-furandione, is an impurity of Dexpanthenol that acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine.

Technology Process of Dexpanthenol iMpurity E

There total 1 articles about Dexpanthenol iMpurity E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isobutyraldehyde (78-84-2) + oxalic acid diethyl ester (95-92-1) → ketopantolactone (13031-04-4) + dihydro-4,4-dimethyl-5-(1-methylethyl)-2,3-furandione (96305-22-5) + pantolactone (79-50-5)

Guidance literature:

With formaldehyd; sodium methylate; Yield given. Multistep reaction. Yields of byproduct given; 1.) methanol, 10 deg C, 20 min, 2.) methanol, 40 deg C, 20 min;

Reference yield:

dihydro-4,4-dimethyl-5-(1-methylethyl)-2,3-furandione (96305-22-5) → 3-methyl-2-ketobutanoic acid (759-05-7)

Guidance literature:

With hydrogenchloride; sodium hydroxide; Yield given. Multistep reaction; 1.) MeOH, 30 deg C, 2 h;

DOI:10.1055/s-1991-26447

upstream raw materials:

isobutyraldehyde

oxalic acid diethyl ester

Downstream raw materials:

3-methyl-2-ketobutanoic acid

Refernces