Cbz-L-alaninol

Base Information

Chemical Name:Cbz-L-alaninol
CAS No.:66674-16-6
Molecular Formula:C₁₁H₁₅NO₃
Molecular Weight:209.245
Hs Code.:2924299090
European Community (EC) Number:822-974-3
DSSTox Substance ID:DTXSID90437508
Nikkaji Number:J57.473B
Wikidata:Q72515926
ChEMBL ID:CHEMBL2259792

Synonyms:66674-16-6;CBZ-L-ALANINOL;(S)-Benzyl (1-hydroxypropan-2-yl)carbamate;N-Z-L-Alaninol;(S)-benzyl 1-hydroxypropan-2-ylcarbamate;BENZYL N-[(2S)-1-HYDROXYPROPAN-2-YL]CARBAMATE;N-Benzyloxycarbonyl-L-alaninol;(S)-benzyl(1-hydroxypropan-2-yl)carbamate;Carbamic acid, [(1S)-2-hydroxy-1-methylethyl]-, phenylmethyl ester;MFCD00672530;N-Cbz-L-alaninol;Z-Ala-ol;benzyl (S)-(1-hydroxypropan-2-yl)carbamate;N-Carbobenzoxy-L-alaninol;N-Z-L-Alaninol, 98%;SCHEMBL1547277;(S)-(2-Hydroxy-1-methylethyl)carbamic acid benzyl ester;CHEMBL2259792;DTXSID90437508;(S)-N-Cbz-2-Amino-1-propanol;AFPHMHSLDRPUSM-VIFPVBQESA-N;(5)-2-benzyloxycarbonylaminopropanol;(S)-2-Benzyloxycarbonylaminopropanol;AKOS016842977;CS-W015162;DS-16421;(S)-2-(Benzyloxycarbonylamino)-1-propanol;C2629;benzyl((S)-2-hydroxy-1-methylethyl)carbamate;benzyl ((S)-2-hydroxy-1-methylethyl)carbamate;benzyl [(1S)-2-hydroxy-1-methylethyl]carbamate;EN300-6296087;A833657;A835517;A850036;J-502483;(phenylmethyl) N-[(2S)-1-oxidanylpropan-2-yl]carbamate;[(1S)-1-(hydroxymethyl)ethyl]carbamic acid benzyl ester;[(1S)-2-hydroxy-1-methylethyl]carbamic acid benzyl ester;benzyl N-[(1S)-2-hydroxy-1-methyl-ethyl]carbamate;Z-D-Dap-OH;N-[(2S)-1-hydroxypropan-2-yl]carbamic acid (phenylmethyl) ester

Suppliers and Price of Cbz-L-alaninol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-L-alaninol
2g
$ 333.00

TRC
(S)-Benzyl(1-Hydroxypropan-2-yl)carbamate
1g
$ 75.00

TCI Chemical
N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N)
1g
$ 27.00

TCI Chemical
N-Carbobenzoxy-L-alaninol >98.0%(HPLC)(N)
5g
$ 81.00

SynQuest Laboratories
Cbz-L-alaninol
25 g
$ 760.00

SynQuest Laboratories
Cbz-L-alaninol
5 g
$ 248.00

Sigma-Aldrich
N-Z-L-Alaninol 98%
5g
$ 260.00

Matrix Scientific
(S)-Benzyl1-hydroxypropan-2-ylcarbamate 97%
5g
$ 357.00

Matrix Scientific
(S)-Benzyl1-hydroxypropan-2-ylcarbamate 97%
25g
$ 1080.00

J&W Pharmlab
N-Z-L-Alaninol 97%
5g
$ 30.00

Total 59 raw suppliers

Chemical Property of Cbz-L-alaninol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:81-84oC
Boiling Point:375.182ºC at 760 mmHg
Flash Point:180.704ºC
PSA：58.56000
Density:1.15g/cm3
LogP:1.68450
Storage Temp.:Store at 0-5°C
Solubility.:Soluble in ethanol.
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:209.10519334
Heavy Atom Count:15
Complexity:190

Purity/Quality:

99%, ^*data from raw suppliers

Z-L-alaninol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CO)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:C[C@@H](CO)NC(=O)OCC1=CC=CC=C1
Uses N-Benzyloxycarbonyl-L-alaninol is used as an important organic intermediate. It is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of Cbz-L-alaninol

There total 26 articles about Cbz-L-alaninol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1142-20-7
N-Cbz-Ala

: 6429-44-3,61425-27-2,87905-97-3,66674-16-6
(S)-(-)-N-(benzyloxycarbonyl)alaninol

Guidance literature:: N-Cbz-Ala; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -15 ℃; for 0.25h;

With sodium tetrahydroborate; In tetrahydrofuran; water; at -15 ℃; for 1h;
DOI:10.1128/AAC.01152-16