(3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole

Base Information

• Chemical Name: (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole
• CAS No.: 1388651-35-1
• Molecular Formula: C₃₁H₂₇F₂NO₃
• Molecular Weight: 499.557

Synonyms:(3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole

Chemical Property of (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole

There total 2 articles about (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2,3-Difluorophenyl)-2-(1-(trityloxy)but-3-en-2-yloxy)ethanone oxime → (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole (1388651-35-1)

Guidance literature:

With hydroquinone; In isopropyl alcohol; toluene;

Reference yield:

tert-butyl methyl ether (1634-04-4) + 1-bromo-2,3-difluorobenzene (38573-88-5) + (3aR*,4S*)-4-((trityloxy)methyl)-3,3a,4,6-tetrahydrofuro[3,4-c]isoxazole → (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole (1388651-35-1)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; water; toluene;

Reference yield:

(3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole (1388651-35-1) + O,O'-dibenzoyl-L-tartaric acid (2743-38-6) → (2S,3R,4S)-(4-amino-4-(2,3-difluorophenyl)-2-((trityloxy)methyl)tetrahydrofuran-3-yl)methanol (-)-dibenzoyl-L-tartaric acid (1388651-04-4)

Guidance literature:

In acetone; at 61.9 ℃; for 0.25h;

upstream raw materials:

tert-butyl methyl ether

1-bromo-2,3-difluorobenzene

Downstream raw materials:

(2S,3R,4S)-(4-amino-4-(2,3-difluorophenyl)-2-((trityloxy)methyl)tetrahydrofuran-3-yl)methanol (-)-dibenzoyl-L-tartaric acid

N-(3-((4aS,5S,7aS)-2-amino-5-(fluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4,5-difluorophenyl)-5-methoxypyrazine-2-carboxamide

N-(((3S,4R,5S)-3-(2,3-difluorophenyl)-4-(hydroxymethyl)-5-((trityloxy)methyl)tetrahydrofuran-3-yl)carbamothioyl)benzamide

N-((4aS,5S,7aS)-7a-(2,3-difluorophenyl)-5-((trityloxy)methyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1388651-35-1 (3aR*,4S*,6aS*)-6a-(2,3-difluorophenyl)-4-((trityloxy)methyl)hexahydrofuro[3,4-c]isoxazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send