Technology Process of 2-(2,2-difluoro-1,3-benzodioxol-4-yl)ethyl benzenesulfonate
There total 3 articles about 2-(2,2-difluoro-1,3-benzodioxol-4-yl)ethyl benzenesulfonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
diethyl ether; water;
at 25 ℃;
for 15h;
DOI:10.1002/ejoc.200390079
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 82 percent / sec-butyllithium; copper(I) iodide / tetrahydrofuran; cyclohexane / 4.75 h / -75 - 25 °C
2: 77 percent / potassium hydroxide / diethyl ether; H2O / 15 h / 25 °C
With
potassium hydroxide; copper(l) iodide; sec.-butyllithium;
In
tetrahydrofuran; diethyl ether; cyclohexane; water;
DOI:10.1002/ejoc.200390079
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 35 percent / butyllithium; potassium tert-butoxide; diisopropylamine / tetrahydrofuran; hexane / 2 h / -75 °C
2: 77 percent / potassium hydroxide / diethyl ether; H2O / 15 h / 25 °C
With
potassium hydroxide; n-butyllithium; potassium tert-butylate; diisopropylamine;
In
tetrahydrofuran; diethyl ether; hexane; water;
DOI:10.1002/ejoc.200390079
