(S)-(+)-N-(2,3-Epoxypropyl)phthalimide

Base Information Edit

Chemical Name:(S)-(+)-N-(2,3-Epoxypropyl)phthalimide
CAS No.:161596-47-0
Molecular Formula:C11H9NO3
Molecular Weight:203.197
Hs Code.:29252900
European Community (EC) Number:454-720-9,605-259-9
UNII:9GA7C6L4S5
DSSTox Substance ID:DTXSID80352110
Nikkaji Number:J2.782.026C
Wikidata:Q72470997
Mol file:161596-47-0.mol

Synonyms:161596-47-0;(S)-N-Glycidylphthalimide;(S)-(+)-N-(2,3-Epoxypropyl)phthalimide;(S)-2-(OXIRAN-2-YLMETHYL)ISOINDOLINE-1,3-DIONE;2-[(2S)-oxiran-2ylmethyl]-1H-isoindole-1,3(2H)-dione;2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione;(s)-glycidyl phthalimide;Glycidyl phthalimide, (S)-;9GA7C6L4S5;(S)-Glycidyl phthalimide [USP-RS];1H-Isoindole-1,3(2H)-dione, 2-[(2S)-oxiranylmethyl]-;1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]-;2-[(2S)-2-oxiranylmethyl]-1H-isoindole-1,3(2H)-dione;2-[(2s)-oxiran-2-ylmethyl]-1h-isoindole-1,3(2h)-dione;N-((S)-(+)-Glycidyl)phthalimide;N-[(S)-(+)-Glycidyl]phthalimide;2-{[(2S)-oxiran-2-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-((2S)-2-oxiranylmethyl)-;MFCD04973350;UNII-9GA7C6L4S5;SCHEMBL78821;N-[(S)-Glycidyl]phthalimide;(S)-( )-Glycidyl Phthalimide;DTXSID80352110;CS-M1834;AKOS016842501;AM84540;GS-3726;(S)-2-oxiranylmethylisoindole-1,3-dione;AC-23326;N-[(2S)-oxiran-2-ylmethyl]-phthalimide;G0328;EC 454-720-9;(S)-2-(oxiran-2-ylmethy)isoindoline-1,3-dione;EN300-7209725;A853175;(S)-2-(oxiran-2-yl methyl)isoindoline-1,3-dione;(S)-2-(oxiran-2-ylmethyl) isoindoline-1,3-dione;2-(((S)-oxiran-2-yl)methyl)isoindoline-1,3-dione;Q-102521;(S)-2-[2-oxiranylmethyl]-1H-isoindole-1,3(2H)-dione;2-[(2S)-2-oxiranylmethyl]-1H-isoindole-1,3(2H)dione;Z1509659015;(S)-2-(oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione;2-[(25)-2-oxiranylmethyl]-1H-isoindole-1,3(2H)-dione;2-[(2S)-2-oxiranylmethyl]-1H-isoindole-1,3-(2H)-dione;2-[(2s)-oxiran-2yl methyl]-1H-isoindole-1,3(2H)dione;N-((2S)-Oxiran-2-ylmethyl)-1H-isoindol-1,3(2H)-dione;(S)-(+)-N-(2,3-Epoxypropyl)phthalimide, >=99.0% (GC);2-{[(2S)-Oxiran-2-yl]methyl}-1H-isoindole-1,3(2H)-dione

Suppliers and Price of (S)-(+)-N-(2,3-Epoxypropyl)phthalimide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(S)-Glycidylphthalimide
25g
$ 215.00

TCI Chemical
(S)-N-Glycidylphthalimide >98.0%(GC)
25g
$ 112.00

TCI Chemical
(S)-N-Glycidylphthalimide >98.0%(GC)
5g
$ 39.00

Sigma-Aldrich
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide ≥99.0% (GC)
1g
$ 26.20

Sigma-Aldrich
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide ≥99.0% (GC)
5g
$ 128.00

Medical Isotopes, Inc.
N-(S)-Glycidylphthalimide
50 g
$ 875.00

Matrix Scientific
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide 97%
100g
$ 800.00

Matrix Scientific
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide 97%
25g
$ 480.00

Matrix Scientific
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide 97%
5g
$ 200.00

Frontier Specialty Chemicals
(S)-N-Glycidylphthalimide 98%
1g
$ 25.00

Total 238 raw suppliers

Chemical Property of (S)-(+)-N-(2,3-Epoxypropyl)phthalimide Edit

Chemical Property:

Vapor Pressure:5.38E-05mmHg at 25°C
Melting Point:102 °C
Refractive Index:10 ° (C=2.2, CHCl3)
Boiling Point:347.4 °C at 760 mmHg
PKA:-2.24±0.20(Predicted)
Flash Point:163.9 °C
PSA：49.91000
Density:1.446 g/cm³
LogP:0.61930
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:203.058243149
Heavy Atom Count:15
Complexity:291

Purity/Quality:

99% ^*data from raw suppliers

N-(S)-Glycidylphthalimide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(O1)CN2C(=O)C3=CC=CC=C3C2=O
Isomeric SMILES:C1[C@@H](O1)CN2C(=O)C3=CC=CC=C3C2=O
Uses N-(S)-Glycidylphthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500).

Technology Process of (S)-(+)-N-(2,3-Epoxypropyl)phthalimide

There total 26 articles about (S)-(+)-N-(2,3-Epoxypropyl)phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 148857-42-5
2-((S)-3-chloro-2-hydroxypropyl)isoindoline-1,3-dione

: 161596-47-0
(S)-N-glycidylphthalimide

Guidance literature:: With sodium carbonate; In 5,5-dimethyl-1,3-cyclohexadiene; for 4h; Reflux; Green chemistry;

Reference yield: 93.6%

: 40137-25-5
1H-isoindole-1,3(2H)-dione, 2-[[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl]

: 161596-47-0
(S)-N-glycidylphthalimide

Guidance literature:: 1H-isoindole-1,3(2H)-dione, 2-[[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl]; With hydrogen bromide; In 1,2-dichloro-ethane; at 10 - 15 ℃; for 4h;

With sodium methylate; In methanol; at 0 - 15 ℃; for 3h;