2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal

Base Information

• Chemical Name: 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal
• CAS No.: 163810-83-1
• Molecular Formula: C₁₅H₁₆O₅S
• Molecular Weight: 308.355
• Mol file: 163810-83-1.mol

Synonyms:2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal

Chemical Property of 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal

There total 5 articles about 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2,5-anhydro-4-O-benzoyl-3,6-di-O-methanesulfonyl-L-idose ethylene acetal (163810-82-0) → 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal (163810-83-1)

Guidance literature:

With sodium hydrogensulfide; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

DOI:10.1016/0008-6215(94)00363-K

Reference yield:

2,5-anhydro-3,6-di-O-methanesulfonyl-L-idose ethylene acetal (153974-01-7) → 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal (163810-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 24 h / Ambient temperature

2: NaSH / dimethylformamide / 40 h / 80 °C

With pyridine; sodium hydrogensulfide; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(99)00492-X

Reference yield:

benzoyl chloride (98-88-4) → 2.5-anhydro-4-O-benzoyl-3,6-thioanhydro-L-talose ethylene acetal (163810-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 24 h / Ambient temperature

2: NaSH / dimethylformamide / 40 h / 80 °C

With pyridine; sodium hydrogensulfide; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(99)00492-X

upstream raw materials:

2,5-anhydro-4-O-benzoyl-3,6-di-O-methanesulfonyl-L-idose ethylene acetal

benzoyl chloride

2,5-anhydro-3,6-di-O-methanesulfonyl-L-idose ethylene acetal

Downstream raw materials:

Benzoic acid (2S,3S,5R)-5-[1,3]dioxolan-2-yl-2-methyl-tetrahydro-furan-3-yl ester

Benzoic acid (2S,3R,5R)-5-[1,3]dioxolan-2-yl-2-methyl-tetrahydro-furan-3-yl ester

Benzoic acid (2S,3S,5R)-5-formyl-2-methyl-tetrahydro-furan-3-yl ester

2,5-anhydro-4-O-benzoyl-3,6-dideoxy-L-lyxo-hexitol