Technology Process of 2,5-anhydro-4-O-benzoyl-1,3,6-trideoxy-1-iodo-L-lyxo-hexitol
There total 7 articles about 2,5-anhydro-4-O-benzoyl-1,3,6-trideoxy-1-iodo-L-lyxo-hexitol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 87 percent / pyridine / 3.5 h / Ambient temperature
2: 67 percent / NaSH monohydrate / dimethylformamide / 4 h / 80 °C
3: 63 percent / H2 / Raney nickel / ethanol / 1.5 h / 80 °C / 760 Torr
4: 6M aq. HCl / trifluoroacetic acid / 24 h / 4 °C
5: NaBH4 / methanol / 0.5 h / Ambient temperature
6: 91 percent / imidazole, Ph3P, I2 / toluene / 2 h / Heating
With
pyridine; 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; sodium hydrogensulfide; hydrogen; iodine; triphenylphosphine;
nickel;
In
methanol; ethanol; N,N-dimethyl-formamide; toluene; trifluoroacetic acid;
DOI:10.1016/0008-6215(94)00363-K
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 63 percent / H2 / Raney nickel / ethanol / 1.5 h / 80 °C / 760 Torr
2: 6M aq. HCl / trifluoroacetic acid / 24 h / 4 °C
3: NaBH4 / methanol / 0.5 h / Ambient temperature
4: 91 percent / imidazole, Ph3P, I2 / toluene / 2 h / Heating
With
1H-imidazole; hydrogenchloride; sodium tetrahydroborate; hydrogen; iodine; triphenylphosphine;
nickel;
In
methanol; ethanol; toluene; trifluoroacetic acid;
DOI:10.1016/0008-6215(94)00363-K
