1-(3,4-Difluorophenyl)piperazine

Base Information

Chemical Name:1-(3,4-Difluorophenyl)piperazine
CAS No.:255893-57-3
Molecular Formula:C10H12F2N2
Molecular Weight:198.215
Hs Code.:2933599090
European Community (EC) Number:674-865-3
DSSTox Substance ID:DTXSID90382443
Nikkaji Number:J1.978.324C
Wikidata:Q72463977
Mol file:255893-57-3.mol

Synonyms:1-(3,4-difluorophenyl)piperazine;255893-57-3;1-(3,4-Difluorophenyl)-piperazine;SCHEMBL478208;DTXSID90382443;VRVIKRZIQWEYFB-UHFFFAOYSA-N;GS1570;MFCD03701086;1-(3,4-Difluoro-phenyl)-piperazine;4-(3,4-Difluoro-phenyl)-piperazine;AKOS009157358;AS-45766;BL008003;A5149;CS-0268925;FT-0690637;EN300-1868307;J-016061

Suppliers and Price of 1-(3,4-Difluorophenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
1-(3,4-Difluorophenyl)-piperazine 97%
5g
$ 285.00

Matrix Scientific
1-(3,4-Difluorophenyl)piperazine 95+%
1g
$ 152.00

Matrix Scientific
1-(3,4-Difluorophenyl)piperazine 95+%
5g
$ 404.00

Atlantic Research Chemicals
1-(3,4-Difluorophenyl)piperazine 95%
1gm:
$ 88.36

American Custom Chemicals Corporation
1-(3,4-DIFLUOROPHENYL)PIPERAZINE 95.00%
5G
$ 1046.61

American Custom Chemicals Corporation
1-(3,4-DIFLUOROPHENYL)PIPERAZINE 95.00%
1G
$ 675.51

AK Scientific
1-(3,4-Difluorophenyl)piperazine
1g
$ 131.00

Total 22 raw suppliers

Chemical Property of 1-(3,4-Difluorophenyl)piperazine

Chemical Property:

Vapor Pressure:0.000579mmHg at 25°C
Refractive Index:1.511
Boiling Point:311 °C at 760 mmHg
Flash Point:141.9 °C
PSA：15.27000
Density:1.193 g/cm³
LogP:1.76820
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:198.09685472
Heavy Atom Count:14
Complexity:183

Purity/Quality:

97% ^*data from raw suppliers

1-(3,4-Difluorophenyl)-piperazine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=CC(=C(C=C2)F)F

Technology Process of 1-(3,4-Difluorophenyl)piperazine

There total 7 articles about 1-(3,4-Difluorophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 646518-38-9
1-benzyl-4-(3,4-difluorophenyl)-piperazine

: 255893-57-3
1-(3,4-difluoro-phenyl)-piperazine

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 64.5h; atmospheric pressure;
DOI:10.1016/j.tetasy.2003.07.024

Reference yield: 96.0%

: tert-butyl 4-(3,4-difluorophenyl)piperazine-1-carboxylate

: 255893-57-3
1-(3,4-difluoro-phenyl)-piperazine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; at 20 ℃; for 4h;

Reference yield: 75.0%

: 348-61-8
1-bromo-3,4-difluorobenzene

: 255893-57-3
1-(3,4-difluoro-phenyl)-piperazine

Guidance literature:: With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; Heating / reflux;