tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt

Base Information

• Chemical Name: tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt
• CAS No.: 1152720-57-4
• Molecular Formula: C₂HF₃O₂*C₁₅H₁₆Br₂N₄O₂
• Molecular Weight: 558.15
• Mol file: 1152720-57-4.mol

Synonyms:tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt

Chemical Property of tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt

There total 1 articles about tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-(3,5-dibromo-4-methoxybenzyl)-5-(N2,N3-bis(tertbutoxycarbonyl)guanidino)azepane-2,4-dione (1152720-55-2) + trifluoroacetic acid (76-05-1) → tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt (1152720-57-4)

Guidance literature:

In dichloromethane; at 25 ℃; for 1h;

DOI:10.1021/ol900709n

Reference yield: 86.0%

tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt (1152720-57-4) → des-methyl ceratamine B (1152720-58-5)

Guidance literature:

With pyridine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 35 ℃; for 1h;

DOI:10.1021/ol900709n

Reference yield: 50.0%

tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt (1152720-57-4) + methyl iodide (74-88-4) → des-Methyl Ceratamine A (1152720-59-6)

Guidance literature:

tetrahydro-des-methyl ceratamine B trifluoroacetic acid salt; With sodium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; at 0 ℃;

methyl iodide; In tetrahydrofuran; N,N-dimethyl-formamide; at -78 - -10 ℃;

upstream raw materials:

3-(3,5-dibromo-4-methoxybenzyl)-5-(N₂,N₃-bis(tertbutoxycarbonyl)guanidino)azepane-2,4-dione

trifluoroacetic acid

Downstream raw materials:

des-methyl ceratamine B

des-Methyl Ceratamine A

tetrahydro-ceratamine B