ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

Base Information

Chemical Name:ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride
CAS No.:1314217-84-9
Molecular Formula:C₁₆H₁₆F₃NO₄*ClH
Molecular Weight:379.763
Hs Code.:

Synonyms:ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

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Chemical Property of ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

Chemical Property:

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Technology Process of ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

There total 4 articles about ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₁₄F₃NO₄

: 1314217-84-9
ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

Guidance literature:: C₁₆H₁₄F₃NO₄; With sodium tetrahydroborate; In toluene; at -5 ℃;

With hydrogenchloride; water; In ethanol;

Reference yield:

: 1314358-28-5
ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate

: 1314217-84-9
ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; water; toluene; at 55 ℃;
DOI:10.1021/op300002f

Reference yield:

: 32365-53-0
ethyl 5-formylfuran-3-carboxylate

: 1314217-84-9
ethyl 5-{[(4-trifluoromethoxybenzyl)amino]methyl}-furan-3-carboxylate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: toluene

2: sodium tetrahydroborate / toluene / -5 °C

With sodium tetrahydroborate; In toluene;