benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate

Base Information

• Chemical Name: benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate
• CAS No.: 111508-34-0
• Molecular Formula: C₁₅H₁₈N₂O₄
• Molecular Weight: 290.319
• Mol file: 111508-34-0.mol

Synonyms:benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate

Chemical Property of benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate

There total 2 articles about benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl ethyl diazene-1,2-dicarboxylate (111508-33-9) + buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) → benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate (111508-34-0)

Guidance literature:

In benzene; for 24h;

DOI:10.1039/P19870000877

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate (111508-34-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / t-butyl hypochlorite / ethyl acetate / 3 h / Ambient temperature

2: 100 percent / benzene / 24 h

With tert-butylhypochlorite; In ethyl acetate; benzene;

DOI:10.1039/P19870000877

Reference yield: 71.0%

benzyl ethyl 1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate (111508-34-0) → 1-ethoxycarbonylhexahydropyridazine (5740-50-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1039/P19870000877

upstream raw materials:

benzyl ethyl diazene-1,2-dicarboxylate

buta-1,3-diene

benzyl chloroformate

Downstream raw materials:

1-ethoxycarbonylhexahydropyridazine

5,6,7,8-tetrahydro-1H,3H-pyrazolo[1,2-a]pyridazine-1,3(2H)-dione